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Bis-3-chloropiperidines: a novel motif for anthelmintic drug design.
RSC Adv
January 2025
Institute of Organic Chemistry, Justus Liebig University 35392 Giessen Germany https://www.uni-giessen.de/de/fbz/fb08/Inst/organische-chemie/AGGoettlich.
Parasites account for huge economic losses by infecting agriculturally important plants and animals. Furthermore, morbidity and death caused by parasites affect a large part of the world population, especially in economically weak regions. Anthelmintic drugs to tackle this challenge remain scarce and their efficiency becomes increasingly endangered by the advent of drug resistance development.
View Article and Find Full Text PDFAn efficient electrocatalytic in-situ hydrogen peroxide generation for ballast water treatment with oxygen groups.
Sci Total Environ
January 2025
Ability R&D Energy Research Centre, School of Energy and Environment, City University of Hong Kong, Hong Kong; State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong.
The in-situ electrochemical production of hydrogen peroxide (HO) offers a promising approach for ballast water treatment. However, further advancements are required to develop electrocatalysts capable of achieving efficient HO generation in seawater environments. Herein, we synthesized two-dimensional lamellated porous carbon nanosheets enriched with oxygen functional groups, which exhibited exceptional performance in HO electrosynthesis.
View Article and Find Full Text PDFSynthesis, Structure and Biological Activity of 2-Methyl-5-nitro-6-phenylnicotinohydrazide-Based Hydrazones.
Molecules
January 2025
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, 1 Alikhanov St., Karaganda 100008, Kazakhstan.
The synthetic availability and wide range of biological activity of hydrazides and hydrazones make them attractive subjects for investigation. In this study, we focused on synthesis of 2-methyl-5-nitro-6-phenylnicotinohydrazide-based hydrazones derived from the corresponding substituted aldehydes. The structure of the obtained compounds was studied using NMR spectroscopy and DFT calculations.
View Article and Find Full Text PDFPreparation of peptides against immunocomplex of deltamethrin and application in noncompetitive lateral flow immunoassay.
Food Chem
January 2025
College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China; State & Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing 210095, China. Electronic address:
Lateral flow immunoassay (LFIA) has the advantages of simplicity and rapidness, and is widely used for the rapid detection of pesticides and other analytes. However, small molecule compounds such as pesticides are often analyzed using competitive LFIA (CLFIA), whose sensitivity often does not meet the actual needs. In this study, a noncompetitive LFIA (NLFIA) for deltamethrin (DM) with high sensitivity was developed by using anti-immunocomplex peptides (AIcPs).
View Article and Find Full Text PDFMicroplastics in soils: A comprehensive review.
Sci Total Environ
January 2025
Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Research Center for Ecology and Environment of Central Asia, Chinese Academy of Sciences, Urumqi 830011, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Microplastics (MPs) have become pervasive pollutants in terrestrial ecosystems, raising significant ecological risks and human health concerns. Despite growing attention, a comprehensive understanding of their quantification, sources, emissions, transport, degradation, and accumulation in soils remains incomplete. This review synthesizes the current knowledge on the anthropogenic activities contributing to soil MP contamination, both intentional and unintentional behaviors, spanning sectors including agriculture, domestic activities, transportation, construction, and industry.
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