Women with diabetes mellitus suffer symptomatic bacteriuria and symptomatic urinary infections more often than non-diabetic women. Prevalence is similar, however, in males with and without diabetes. There is a controversy on the impact of asymptomatic bacteriuria on the development of complications in diabetic patients. Current evidence is reviewed concerning the need for detection and treatment of asymptomatic bacteriuria in these patients.
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http://dx.doi.org/10.1157/13074164 | DOI Listing |
NEJM Evid
February 2025
Department of Microbiology, Sinai Health and University Health Network, Toronto.
AbstractScreening and treatment of asymptomatic bacteriuria is generally not recommended due to a lack of clinical benefit and potential harm. A notable exception is the recommendation for routine screening during pregnancy. In this Tomorrow's Trial, the authors review the relevant evidence and propose a trial to address the question, "should low-risk pregnant patients be screened for asymptomatic bacteriuria?"
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Nephrology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 1200 Brussels, Belgium.
Urinary tract infections (UTIs) are a common complication after kidney transplantation. The aim of this study was to evaluate the impact of pre-existing diabetes mellitus and post-transplant diabetes mellitus (PTDM) on the occurrence of pyelonephritis in kidney transplant recipients. We performed a retrospective analysis which included 299 adult patients transplanted with a kidney between 2018 and 2022.
View Article and Find Full Text PDFAm J Infect Control
January 2025
Division of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. Electronic address:
Background: The rate of antibiotic treatment for catheter-associated asymptomatic bacteriuria (CA-ASB) remains high.
Methods: We conducted a retrospective study involving hospitalized patients with multidrug-resistant Pseudomonas aeruginosa (MDRP) CA-ASB. Cox proportional hazards regression models were used to identify predictors for subsequent symptomatic infections in patients with MDRP CA-ASB.
SAGE Open Med
January 2025
Department of Obstetrics and Gynecology, Dr. Hasan Sadikin General Hospital Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia.
Introduction: Urinary tract infections are prevalent among pregnant women and can lead to serious maternal and neonatal complications. Hypertensive disorders of pregnancy, a leading cause of maternal morbidity, may be associated with urinary tract infections. This study investigates whether bacteriuria detected via routine urinalysis, a standard screening in Indonesia, contributes to hypertension risk during pregnancy, aiming to enhance clinical management and screening protocols.
View Article and Find Full Text PDFClin Infect Dis
January 2025
Infection Control, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Background: Urinary tract infections are prone to overdiagnosis, and reflex urine culture protocols offer a valuable opportunity for diagnostic stewardship in this arena. However, there is no recommended standard testing approach. Cancer patients are often excluded from reflex urine culture protocols, especially if severely immunosuppressed or neutropenic.
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