The effects of dietary naringenin supplementation on physiological changes in molar crestal alveolar bone-cemento-enamel junction distance in young rats.

The objective of this study was to evaluate the influence of dietary naringenin (NAR) supplementation on physiological molar crestal alveolar bone (CAB)-cemento-enamel junction (CEJ) distances in young male albino rats. The effects of diets supplemented with 0.09%, 0.18%, 0.36%, and 0.72% NAR, at the expense of dextrose, were tested on 40 young rats, divided equally into five groups, for a period of 42 days. Rat skulls were defleshed, and CAB-CEJ distance was scored according to the modified method of Keyes and Gold. Data were analyzed using one-way analysis of variance, post hoc Tukey's test, and Spearman's (R(2)) correlation. P < .05 was used to reject the null hypothesis. NAR showed a statistically significant inverse dose-dependent relationship on CAB-lingual alveolar bone distance (P < .05). In all cases lingual CAB-CEJ distance was larger than buccal CAB-CEJ distance. Thus dietary NAR supplementation was shown to significantly reduce molar CAB-CEJ distance (P < .001-.05) during alveolar development in young male rats.