The effect of drying conditions on harpagoside (HS) retention, as well as the use of near-infrared spectroscopy (NIRS) for rapid quantification of the iridoids, HS, and 8-rho-coumaroyl harpagide (8rhoCHG) and moisture, in dried Harpagophytum procumbens (devil's claw) root was investigated. HS retention was significantly (P < 0.05) lower in sun-dried samples as compared to tunnel-dried (60 degrees C, 30% relative humidity) and freeze-dried samples. The best retention of HS was obtained at 50 degrees C when evaluating tunnel drying at dry bulb temperatures of 40, 50, and 60 degrees C and 30% relative humidity. NIRS can effectively predict moisture content with a standard error of prediction (SEP) and correlation coefficient (r) of 0.24% and 0.99, respectively. The HS and 8rhoCHG NIRS calibration models established for both iridoid glucosides can be used for screening purposes to get a semiquantitative classification of devil's claw roots (for HS: SEP = 0.236%, r = 0.64; for 8rhoCHG: SEP = 0.048%, r = 0.73).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jf047930c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of pretreatment with Devil's Claw on locomotor activity, infarct volume, and neuronal density in focal cerebral ischemia in rats.
Avicenna J Phytomed
January 2024
Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Objective: Stroke is a highly prevalent and devastating condition affecting millions worldwide. The Devil's Claw (DCW) plant is a native African plant whose anti-inflammatory, antioxidant, and neuroprotective properties have been investigated. We postulated that DCW could protect the brain injury caused by cerebral ischemia.
View Article and Find Full Text PDFOsteoarthritis: Insights into Diagnosis, Pathophysiology, Therapeutic Avenues, and the Potential of Natural Extracts.
Curr Issues Mol Biol
April 2024
Department of Experimental Medicine, University of Salento, Via Lecce-Monteroni, 73100 Lecce, Italy.
Osteoarthritis (OA) stands as a prevalent and progressively debilitating clinical condition globally, impacting joint structures and leading to their gradual deterioration through inflammatory mechanisms. While both non-modifiable and modifiable factors contribute to its onset, numerous aspects of OA pathophysiology remain elusive despite considerable research strides. Presently, diagnosis heavily relies on clinician expertise and meticulous differential diagnosis to exclude other joint-affecting conditions.
View Article and Find Full Text PDFA Systemic Review on Nutraceutical Supplements used in the Management of Osteoarthritis.
Recent Adv Food Nutr Agric
June 2024
Department of Biotechnology, Integral Informatic and Research Center-1 (IIRC-1) Intergral University Lucknow Uttar Pradesh-226026, India.
Osteoarthritis (OA) is a progressive degenerative joint disease. It basically impairs the structural integrity of articulate cartilage and imbalances the catabolic and anabolic signals in the joint. A degenerative disease is characterized by swelling, pain, and joint stiffness.
View Article and Find Full Text PDFOpen, Observational, Single-Arm, Multicenter Study Assessing the Effectiveness of a Dietary Supplement Containing Hydrolyzed Collagen, Chondroitin Sulfate, and Glucosamine for Osteoarthritis Pain Reduction.
J Diet Suppl
April 2024
Traumatology and Sports Surgery Department, Centre for Sports Medicine, Traumatology and Rehabilitation, Clinic Sant Josep, Manresa, Barcelona, Spain.
Osteoarthritis (OA) is an age-related degenerative joint disease with a great impact on patients' well-being and quality of life. This is an observational, open, single-arm multicenter study aimed to evaluate the effectiveness of a nutritional supplement in patients with knee and/or hip OA. A total of 186 patients were recruited from Spanish centers and received a supplement containing hydrolyzed collagen (3000 mg), chondroitin sulfate (800 mg), glucosamine sulfate (700 mg), turmeric extract (250 mg) and devil's claw (150 mg), once daily during 6 months.
View Article and Find Full Text PDFEthyl Acetate Fraction of Harpagophytum procumbens Prevents Oxidative Stress In Vitro and Amphetamine-Induced Alterations in Mice Behavior.
Neurochem Res
June 2023
Departamento de Morfologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.
Microglial activation has been associated to the physiopathology of neurodegenerative diseases, such as schizophrenia, and can occur during inflammation and oxidative stress. Pharmacological treatment is associated with severe side effects, and studies for use of plant extracts may offer alternatives with lower toxicity. Harpagophytum procumbens (HP) is a plant known for its anti-inflammatory properties.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!