[Neurotransmitter stage in the development of peripheral part of autonomic nervous system].

The dynamics of neurotransmitter stage in the development of autonomic nervous system (ANS) was studied in rats starting from the moment of initial appearance of neurotransmitters acetylcholine and adrenalin in ANS peripheral part main nervous plexuses. Cryostat sections of embryos on developmental days 13.5, 16.5 and 18.5 and of neonatal rats aged 0.5 and 1.5 days were treated with glyoxilic acid, using Karnovsky-Roots method and impregnated with silver nitrate according to Bielschowsky-Gross method. Acetylcholinesterase in vagus and in spinal ganglia was found on day 13.5, while catecholamine in sympathetic trunc was detected in animals immediately after the birth. Periods of the beginning of neurotransmitter stage in ANS development in rat and man were compared and it was established that it was delayed in rat as in immature-born animal.