Larval Echinococcus granulosus infection (hydatid cyst) was reported in a 10 years-old Ukranian girl. The clinical manifestations were slight since she only complained of frequent abdominal pain. The diagnosis was made by ultrasound and immunoenzymatic detection of antibodies to Echinococcus (ELISA). Antibody titers were 1/800. She was repeatedly treated with albendazol, and she managed to recover while the size of her cyst was reduced.
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Front Parasitol
January 2025
World Organisation for Animal Health (WOAH) and National Reference Laboratory for Echinococcosis, Istituto Zooprofilattico della Sardegna, Sassari, Italy.
Cystic echinococcosis (CE) is a zoonotic disease caused by sensu lato, the metacestode of a tapeworm parasite of high medical importance. Infection of the parasite leads to the development of echinococcal cysts, and the spleen is a rarely infected organ. A 46-year-old woman who was born and who resides in Sardinia, Italy, was referred to the Echinococcosis outpatient clinic at the University Hospital of Sassari (Sardinia, Italy) for a pain in the left flank.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Radiology, Mohammed VI University Hospital, Faculty of Medicine, University Mohammed First, Oujda, Morocco.
Echinococcosis, or hydatid disease, is an endemic disease that affects many regions worldwide and remains a significant public health issue in areas with high endemicity. It is caused by an infection with the dog tapeworm *Echinococcus granulosus*, which is transmitted to humans either through direct contact with dogs or by ingesting contaminated food. This disease primarily affects internal organs, particularly the liver and lungs.
View Article and Find Full Text PDFJ Gastrointest Surg
January 2025
Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.
Introduction: Cystic echinococcosis is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm, which is transmitted by dogs and found on every continent except Antarctica. We sought to review the life cycle, epidemiology, symptoms, diagnostic methods, and treatment of Echinococcus granulosus of the liver.
Methods: A comprehensive review was conducted using Medline/PubMed, Google Scholar, Cochrane Library, and the Web of Science accessed between 1990 and 2024.
Viruses
December 2024
School of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.
Canids act as a crucial intermediary in the transmission of rabies and , serving as co-infection hosts and pathogen carriers for both rabies and hydatid disease (HD) transmitted from animals to humans. Therefore, an effective and efficient bivalent oral vaccine for preventing HD and rabies is urgently required to reduce economic losses in husbandry resulting from rabies and HD. In this study, a full-length plasmid (pcDNA4-NPM+G+EgM123+eGFP+L) carrying the gene and fluorescence reporter genes of eGFP and four auxiliary transfection plasmids of rabies virus SRV (pcDNA4-N, pcDNA4-P, pcDNA4-G, pcDNA-L) were established by reverse genetics approaches and co-transfected to BSR cells by electrotransfection.
View Article and Find Full Text PDFPathogens
January 2025
Department of Microbiology and Immunology, Faculty of Pharmacy, "Ovidius" University of Constanta, Str. Căpitan Aviator Al. Șerbănescu, nr.6, Campus Corp C, 900470 Constanta, Romania.
Cystic echinococcosis (CE) is a neglected tropical parasitic disease linked with significant social and economic burdens worldwide. The scientific community has minimal information on echinococcosis in Romanian people, and hospital medical records are the only sources that may be used to investigate its status. A 7-year retrospective clinical study on pediatric patients with CE from Southeast Romania was performed, and 39 children and adolescents were included, aged 2-15 years old.
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