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The New Italian Guidelines for Assisted Reproduction Technologies (ART): Ethical and Medico-Legal Issues.
Healthcare (Basel)
January 2025
Department of Health Care Surveillance and Bioethics, Section of Bioethics and Medical Humanities, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy.
On 20 March 2024, the Italian Minister of Health, in collaboration with the Italian National Institute of Health (Istituto Superiore di Sanità) and the National Health Council (Consiglio Superiore di Sanità), issued updated guidelines for assisted reproduction technologies (ART). They introduced two key changes: (1) permitting post-mortem embryo transfers, allowing a woman to proceed with the procedure after her male partner's death, and (2) permitting embryo transfer even if the male partner is alive but the relationship has ended. : This study explores the ethical and medico-legal challenges posed by the updated Italian ART Guidelines, with a specific focus on the complexities of informed consent and the ethical dilemmas introduced by these provisions.
View Article and Find Full Text PDFExplainable AI in Diagnostic Radiology for Neurological Disorders: A Systematic Review, and What Doctors Think About It.
Diagnostics (Basel)
January 2025
Aerospace Engineering Department and Interdisciplinary Research Center for Smart Mobility and Logistics, and Interdisciplinary Research Center Aviation and Space Exploration, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
Artificial intelligence (AI) has recently made unprecedented contributions in every walk of life, but it has not been able to work its way into diagnostic medicine and standard clinical practice yet. Although data scientists, researchers, and medical experts have been working in the direction of designing and developing computer aided diagnosis (CAD) tools to serve as assistants to doctors, their large-scale adoption and integration into the healthcare system still seems far-fetched. Diagnostic radiology is no exception.
View Article and Find Full Text PDFFeasibility pilot of a novel coaching intervention to optimize cannabis use for chronic pain management among Veterans.
J Cannabis Res
January 2025
Anesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, 48105, USA.
Introduction: Chronic pain is common among Veterans, some of whom use cannabis for pain. We conducted a feasibility pilot study of a novel coaching intervention to help Veterans optimize use of medical cannabis products for pain management (NCT06320470).
Methods: The intervention drew from scientific literature, consultation with cannabis experts, Veteran input via a Community Advisory Board, and tenets of motivational interviewing.
Spatial transcriptome reveals histology-correlated immune signature learnt by deep learning attention mechanism on H&E-stained images for ovarian cancer prognosis.
J Transl Med
January 2025
Department of Gynecologic Oncology and Reproductive Medicine, Unit 1362, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
Background: The ability to predict the prognosis of patients with ovarian cancer can greatly improve disease management. However, the knowledge on the mechanism of the prediction is limited. We sought to deconvolute the attention feature learnt by a deep learning convolutional neural networks trained with whole-slide images (WSIs) of hematoxylin-and-eosin (H&E)-stained tumor samples using spatial transcriptomic data.
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