The concentration of apolipoprotein A-I decreases during experimentally induced acute-phase processes in pigs.

Infect Immun

Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain.

Published: May 2005

In this work, apolipoprotein A-I (ApoA-I) was purified from pig sera. The responses of this protein after sterile inflammation and in animals infected with Actinobacillus pleuropneumoniae or Streptococcus suis were investigated. Decreases in the concentrations of ApoA-I, two to five times lower than the initial values, were observed at 2 to 4 days. It is concluded that ApoA-I is a negative acute-phase protein in pigs.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087351PMC
http://dx.doi.org/10.1128/IAI.73.5.3184-3187.2005DOI Listing

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