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Modulation of morphine antinociceptive and rewarding effect by mirtazapine in an animal model of osteoarthritic pain.
Eur J Pharmacol
January 2025
Area of Pharmacology, Nutrition and Bromatology, Department of Basic Health Sciences, Rey Juan Carlos University (URJC), Associated R+D+i Unit to the Institute of Medicinal Chemistry (IQM), Scientific Research Superior Council (CSIC), Alcorcón, Spain; High Performance Research Group in Experimental Pharmacology (PHARMAKOM) of the Rey Juan Carlos University, Alcorcón, Spain.
People with chronic pain mitigate their suffering by the action of opioids. Adverse reactions aside, opioids are not exempt from potential complications like addiction and abuse, which have posed a global public health problem lately. Finding new therapeutic strategies to improve analgesia and to reduce opioid side effects has become a priority.
View Article and Find Full Text PDFMirtazapine: An Antidepressant for Treating Chronic, Refractory Nausea and Vomiting in a Patient With Metastatic Sarcoma Receiving Palliative Care: A Case Report.
Clin Case Rep
November 2024
Cancer Research Center Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences Tehran Iran.
Managing chronic, refractory nausea and vomiting in advanced cancer patients is challenging, especially when unrelated to cancer treatment. Mirtazapine, a tetracyclic antidepressant, effectively alleviates these symptoms, improving quality of life. It offers a promising palliative care alternative, addressing multiple symptoms and reducing polypharmacy, thereby enhancing patient satisfaction.
View Article and Find Full Text PDFMirtazapine-Associated Hyperkinetic Movements in a 17-Year-Old with Autism Spectrum Disorder and Chronic Catatonia: A Case Report.
J Child Adolesc Psychopharmacol
November 2024
The Pritzker Department of Psychiatry and Behavioral Health, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Mirtazapine for gastrointestinal and neuropsychological symptoms in older adults with irritable bowel syndrome.
Therap Adv Gastroenterol
October 2024
Division of Geriatrics and Palliative Medicine, University of Texas at Medical Branch, Galveston, TX, USA.
Irritable bowel syndrome (IBS) is a common and potentially modifiable contributor to excess disability, morbidity, and poor quality of life. Clinical trials of medications for IBS have largely been in younger adults. Yet, a growing number of adults aged 65 and older are living with IBS.
View Article and Find Full Text PDFStroke Mimics: A Case of John Cunningham Virus-Induced Progressive Multifocal Leukoencephalopathy.
Cureus
September 2024
Stroke, Russells Hall Hospital, Dudley, GBR.
Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal neurological disorder caused by the John Cunningham virus (JCV). It affects immunocompromised individuals, leading to brain demyelination. Diagnosis involves MRI scans and JCV detection in cerebrospinal (CSF) fluid.
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