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Objective: The leptomeningeal ivy sign is a distinctive finding of moyamoya disease (MMD), characterized by a linear high signal intensity along the cortical sulci on contrast-enhanced T1 magnetic resonance imaging (MRI) and fluid-attenuated inversion-recovery MRI. We recently identified a similar linear enhancement along the cortical sulci using gadolinium-enhanced vessel wall MRI (VWMR) in patients with MMD. The aim of this study was to introduce the concept of the "VWMR ivy sign (VIS)".

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Aims: WNT signalling pathway dysregulation is often a critical early component in colorectal neoplasia, particularly the chromosomal instability pathway. Using two WNT reporters, and , we sought to assess whether these polyps demonstrate predictable expression patterns and if these patterns show diagnostic value.

Methods: We evaluated 23 adenomas (TA), 23 sessile serrated lesions (SSLs), 14 SSL with dysplasia and 38 traditional serrated adenomas (TSA).

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Multi-pass cavity-enhanced Raman spectroscopy of complex natural gas components.

Anal Chim Acta

January 2025

State Key Laboratory of Power Transmission Equipment Technology (Chongqing University), Chongqing, 400044, China; National Innovation Center for Industry-Education Integration of Energy Storage Technology, China. Electronic address:

Background: The concentration of natural gas components significantly impacts the transportation, storage, and utilization of natural gas. Consequently, implementing online monitoring and leak detection systems is vital to guarantee the efficient use of natural gas and to uphold its safe and stable operation. Raman spectroscopy offers distinctive benefits, including high selectivity, superior precision, and the capability to detect multiple gas components simultaneously using a single-wavelength laser.

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Low-potential bionic electrochemiluminescence sensing platform based on SnS/CuNWs synergistic promotion for highly selective detection of glycocholic acid.

Anal Chim Acta

January 2025

Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China. Electronic address:

Background: Glycholic acid (GCA) can dynamically reflect the process of liver injury, and can be used for early diagnosis and curative effect evaluation of early hepatitis and cirrhosis. The highly sensitive detection of liver injury markers is conducive to a more accurate and effective auxiliary diagnosis of liver diseases. In addition, the low trigger potential helps to avoid more chemical interference and improve the detection sensitivity.

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Dual-stage excitation source improves the analytical sensitivity of miniaturized optical emission spectrometer.

Talanta

January 2025

Department of Chemistry, School of Forensic Medicine, China Medical University, Shenyang, 110122, China. Electronic address:

Miniaturized optical emission spectrometric (OES) devices based on various microplasma excitation sources provide a reliable tool for in-situ elemental analysis. The key to improving analytical performance is enhancing the excitation capability of the microplasma source in these devices. Here, dielectric barrier discharge (DBD) and point discharge (PD) technologies are combined to construct an enhanced dual-stage excitation source (called DBD-PD), which improves the overall excitation efficiency and OES signal sensitivity.

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