Di Yi Jun Yi Da Xue Xue Bao
Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Published: April 2005
Objective: To establish a method by high-performance liquid chromatography (HPLC) for determining the concentration of magnetic mitomycin C-polybutylcyanoacrylate nanoparticles in mouse plasma.
Methods: Chromatography was performed on a LiChroCART C18 (250 mm x 4 mm, 5 microm) column with the mobile phase consisting of acetonitrile-NaAC (15:85), the flow rate of 1.0 ml/min, and the detection wavelength of 365 nm. Sample extraction was carried out with ethylacetate.
Results: The linear range of mouse plasma mitomycin C concentration was 0.04-1.00 microg/ml, and the linear equation of Y=16 388X-17.17 (r=0.999 8) was derived.
Conclusion: This method is very easy to operate and suits the need of perclinical pharmacokinetic studies of mitomycin-magnetic nanoparticles and yields accurate and precise results.
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ACS Appl Bio Mater
October 2024
Department of Mechanical Engineering, Indian Institute of Technology Kanpur, Kanpur 208016, India.
For better bone regeneration, precise control over the architecture of the scaffolds is necessary. Because the shape of the pore may affect the bone regeneration, therefore, additive manufacturing has been used in this study to fabricate magnetic bioactive glass (MBG) scaffolds with three different architectures, namely, grid, gyroid, and Schwarz D surface with 15 × 15 × 15 mm dimensions and 70% porosity. These scaffolds have been fabricated using an in-house-developed material-extrusion-based additive manufacturing system.
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February 2024
Department of Mechanical Engineering, Indian Institute of Technology Kanpur, Kanpur 208016, India.
In this study, we have synthesized a bioactive glass with composition 45SiO-20NaO-23CaO-6PO-2.5BO-1ZnO-2MgO-0.5CaF (wt %).
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Department of Ophthalmology, Bangalore Medical College and Research Institute, India.
Head and neck cancers (HNCs) present a significant global health burden, especially in India, where oral cavity cancers, notably affecting the tongue, are prevalent. A substantial portion of global HNCs (57.5%) is concentrated in Asia, India contributing with 30%.
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Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Curr Oncol
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Department of Urology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
This review article gives an overview of the current state of the art of bladder cancer imaging and then discusses in depth the scientific and technical merit of a novel imaging approach, tracing its evolution from murine cancer models to cancer patients. While the poor resolution of soft tissue obtained by widely available imaging options such as abdominal sonography and radiation-based CT leaves them only suitable for measuring the gross tumor volume and bladder wall thickening, dynamic contrast-enhanced magnetic resolution imaging (DCE MRI) is demonstrably superior in resolving muscle invasion. However, major barriers still exist in its adoption.
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