This paper examines the drinking habits of a Northern Irish sample during a six-month period in 1998. In addition the study examines the influence of contextual variables on the quantity and frequency of alcohol consumption. Questionnaires were administered to 600 participants; the response rate was 39.8% (239). An unexpected low abstinence rate was observed that, however, may be due to response bias. The results revealed high frequency (29.7% drink on four or more days a week) and high quantity of alcohol consumption (mean units per week 43.21, SD 40.33). Beer drinkers consumed the largest quantity of alcohol and also had the highest frequency of alcohol consumption. It was observed that 45.8% of all drinking events took place in a public bar and the popularity of the public bar for alcohol consumption was not influenced by age or gender. The present investigation revealed that almost half (45%) of individuals consume more than one type of beverage at one sitting, and there is a trend of consuming alcohol in more than one place during a single drinking session. These results indicate a distinctive drinking pattern within Northern Ireland and have implications for studies investigating the effects of alcohol on the social drinker.
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Sci Rep
January 2025
College of Clinical Laboratory, Changsha Medical University, Changsha, Hunan, China.
To evaluate the clinical utility of PCT, CRP, IL-6, NLR, and TyG index in improving the early diagnosis and severity assessment of acute pancreatitis (AP). This retrospective study included 137 AP patients and 30 healthy controls from Hunan Provincial People's Hospital (January 2021-September 2023). Univariate and multivariate logistic regression analyses assessed the associations between biomarkers and severe acute pancreatitis (SAP).
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January 2025
Department of Psychology (Scarborough), University of Toronto, Toronto, ON, Canada.
Recent research has identified sex-dependent links between risk taking behaviors, approach-avoidance bias and alcohol intake. However, preclinical studies have typically assessed alcohol drinking using a singular dimension of intake (i.e.
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January 2025
Department of Cardiology, Euroclinic Hospital, Athens, Greece; First Department of Cardiology, Athens University School of Medicine, Athens, Greece. Electronic address:
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty-liver disease, is an important and rising health issue with a link with atherosclerotic cardiovascular (CV) disease (CVD), affecting ∼25-30% of the adults in the general population; in patients with diabetes, its prevalence culminates to ∼70%; its evolutive form, nonalcoholic steatohepatitis, is estimated to be the main cause of liver transplantation in the future. MASLD is a multisystem disease that affects, besides the liver, extra-hepatic organs and regulatory pathways; it raises the risk of type 2 diabetes mellitus (T2D), CVD, and chronic kidney disease; the disease may also progress to hepatocellular carcinoma. Its diagnosis requires hepatic steatosis and at least one cardiometabolic risk factor and the exclusion of both significant alcohol consumption and other competing causes of chronic liver disease.
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Department of Pharmacology and Toxicology, Faculty of Pharmacy, Kaferelsheikh University, Kaferelsheikh, Egypt. Electronic address:
Alcoholic liver disease (ALD) is a commonly known liver disease mediated by prolonged alcohol consumption. Aescin is a triterpene saponin that can manage several conditions, including brain trauma, arthritis, venous congestion, stroke, and thrombophlebitis. Even so, studies illustrating the aescin role in ALD are scarce.
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January 2025
Department of Neurology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background: The hypothalamus is involved in stress regulation and reward processing, with its various nuclei exhibiting unique functions and connections. However, human neuroimaging studies on the hypothalamic subregions are limited in drug addiction. This study examined the volumes and functional connectivity of hypothalamic subregions in individuals with alcohol use disorder (AUD).
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