A method to detect production faults in flexible plastic packages with the use of terahertz radiation is presented. Relying on the large difference between the absorption coefficients of plastic and water (for water-filled channel defects) and on the refraction index difference between plastic and air (for air-filled channel defects), our technique consists of focusing and scanning a terahertz beam on the sealed area of the package, followed by detection of the transmitted signal. Compared with previous methods, such as visual and ultrasound inspection, our technique can be applied to optically opaque packages and does not require immersion in a matching liquid. We tested our system on defects that we fabricated as water-filled and air-filled channels imbedded in polyethylene films, with diameters in the range of 10 to 100 microm. The detection limit (the minimum size of a detectable defect) depends on the conveying speed; this relationship was determined and analyzed. The results show that our system has the potential for application in an actual production line for real-time inspection.
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http://dx.doi.org/10.4315/0362-028x-68.4.833 | DOI Listing |
Int J Pharm
January 2025
Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, 9000 Gent, Belgium. Electronic address:
Cosmetic inspection of freeze-dried products is an important part of the post-manufacturing quality control process. Traditionally done by human visual inspection, this method poses typical challenges and shortcomings that can be addressed with innovative techniques. While many cosmetic defects can occur, some are considered more critical than others as they can be harmful to the patient or affect the drug's efficacy.
View Article and Find Full Text PDFPLoS One
January 2025
Logistics service company, Civil Aviation Flight University of China, Guanghan, Sichuan, China.
The risk assessment and prevention in traditional airport safety assurance usually rely on human experience for analysis, and there are problems such as heavy manual workload, excessive subjectivity, and significant limitations. This article proposed a risk assessment and prevention mechanism for airport security assurance that integrated LSTM algorithm. It analyzed the causes of malfunctioning flights by collecting airport flight safety log datasets.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China.
Portable sensor technologies are indispensable in personalized healthcare and environmental monitoring as they enable the continuous tracking of key analytes. Human sweat contains valuable physiological information, and previously developed noninvasive sweat-based sensors have effectively monitored single or multiple biomarkers. By successfully detecting biochemicals in sweat, portable sensors could also significantly broaden their application scope, encompassing non-biological fluids commonly encountered in daily life, such as mineral water.
View Article and Find Full Text PDFSci Rep
January 2025
Nanchang Institute of Technology, Nanchang, 330099, China.
Drone inspections are widely utilized in the detection of insulators in power lines. To address issues with traditional object detection algorithms, such as large parameter counts, low detection accuracy, and high miss rates, this paper proposes an insulator detection algorithm based on an improved YOLOv5 model. Firstly, in the backbone and neck networks, a lightweight CSP-SCConv module is employed to replace the original CSP-Darknet53 module, thereby reducing the parameter count and enhancing the feature extraction capabilities.
View Article and Find Full Text PDFJ Chromatogr B Analyt Technol Biomed Life Sci
December 2024
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China. Electronic address:
For separation of deoxyribonucleic acid (DNA), positively charged amino-modified magnetic nanoparticles (MN) can effectively adsorb negatively charged DNA through electrostatic interaction. However, the reported preparation of amino-modified MN is usually tedious and time-consuming. Therefore, a simple synthesis method of amino-modified MN is necessary for DNA extraction.
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