Diabetic pregnancy: evidence of selection on the Rh blood group system.

Hum Biol

Division of Biometry and Human Development, School of Medicine, 2d University of Rome, Italy.

Published: February 1992

The blood glucose levels of pregnant women with insulin-dependent diabetes mellitus and the blood glucose levels of newborns during the first few hours of life show an association with maternal Rh genotype. Distortions of joint maternal-fetal Rh phenotype distribution have also been observed. Because a cluster of genes involved in glycide metabolism is located on the short arm of chromosome 1, the present observations may reflect the action of these genes.

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