The authors investigated the role of visuo-spatial attention in an antisaccade task using event-related potentials (ERPs) in schizophrenia patients compared to healthy controls. ERPs between 80-130 ms (P100) after stimulus onset showed differences between pro- and antisaccades only for controls and can be related to the suppression of irrelevant stimulus features. Between 150-180 ms (N100), a larger amplitude for anti-compared to prosaccades over centroparietal electrodes showed that processes of visuo-spatial attention seem to be engaged in performance of the antisaccade task. Left temporo-occipitally, this activity was only evident in schizophrenia patients, possibly reflecting additional neuronal recruitment in order to perform the antisaccade task successfully.
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http://dx.doi.org/10.1080/00207450590887475 | DOI Listing |
Mult Scler Relat Disord
January 2025
Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Background: Oculomotor abnormalities are common in multiple sclerosis (MS) but are not quantitatively evaluated in clinical practice. Oculometric measures (OMs) are characteristics of eye movements captured while performing a visual task, e.g.
View Article and Find Full Text PDFJ Transl Med
January 2025
School of Information and Communication Engineering, Dalian University of Technology, No. 2 Linggong Road, 116024, Dalian, China.
Background: Parkinson's Disease (PD) is a neurodegenerative disorder, and eye movement abnormalities are a significant symptom of its diagnosis. In this paper, we developed a multi-task driven by eye movement in a virtual reality (VR) environment to elicit PD-specific eye movement abnormalities. The abnormal features were subsequently modeled by using the proposed deep learning algorithm to achieve an auxiliary diagnosis of PD.
View Article and Find Full Text PDFBehav Res Methods
January 2025
Department Neurophysics, Philipps-Universität Marburg, Fachbereich Physik, AG Neurophysik, Karl-Von-Frisch-Straße 8a, 35043, Marburg, Lahnberge, Germany.
The analysis of eye movements is a noninvasive, reliable and fast method to detect and quantify brain (dys)function. Here, we investigated the performance of two novel eye-trackers-the Thomas Oculus Motus-research mobile (TOM-rm) and the TOM-research stationary (TOM-rs)-and compared them with the performance of a well-established video-based eye-tracker, i.e.
View Article and Find Full Text PDFNPJ Parkinsons Dis
December 2024
Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.
Oculomotor behaviour changes in patients with Parkinson's disease (PD) are a promising source of prodromal disease markers. Capitalizing on this phenomenon to facilitate early diagnosis requires oculomotor assessment in prodromal cohorts. We examined oculomotor behaviour in non-manifesting LRRK2 G2019S mutation carriers (LRRK2-NM), who have heightened PD risk.
View Article and Find Full Text PDFPsychophysiology
January 2025
Department of Psychology and Research Institute for Health Sciences (iUNICS), University of the Balearic Islands, Palma, Spain.
Unexpected sounds have been shown to trigger a global and transient inhibition of motor responses. Recent evidence suggests that eye movements may also be inhibited in a similar way, but it is not clear how quickly unexpected sounds can affect eye-movement responses. Additionally, little is known about whether they affect only voluntary saccades or also reflexive saccades.
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