AI Article Synopsis
- A study involving 20 patients with atopic dermatitis compared two UVB treatment methods: conventional fixed dosages versus dosages guided by skin reflectance measurements of pigmentation and erythema.
- Both treatments showed no significant difference in the reduction of SCORAD scores, but the skin reflectance-guided method resulted in significantly lower final and cumulative UVB dosages.
- This innovative technique is as effective and safe as traditional methods and can be easily implemented by nurses due to its rapid measurement process.
Article Abstract
In a randomized, open, left-right comparison study, 20 patients with atopic dermatitis were treated with UVB. One side of the body received UVB in a conventional regimen with fixed dosage increments, the other side was given UVB dosages according to skin reflectance measurements of skin pigmentation and erythema. Clinical outcome was assessed by SCORAD. The initial, final and cumulative UVB dosages, time to 50% reduction in SCORAD, and side effects were compared. The initial UVB dosage was somewhat higher in the skin reflectance-guided treatment than in the conventional UVB regimen, although not significantly. There was no difference in the reduction of SCORAD comparing the two treatment options; however, the final UVB dosage and the cumulative UVB dosages were significantly lower in the optimized regimen. This new technique offers the same therapeutic advantage and security as a dose regimen guided by minimal erythema dose testing. However, measurement of skin pigmentation by skin reflectance is a rapid method, which can easily be operated by nurses.
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| http://dx.doi.org/10.1080/00015550410024085 | DOI Listing |
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