On the basis of the analysis of clinical and experimental data a conclusion is made about existence of the regulatory-metabolic relations between different elements of the placenta and organs and tissues of the fetus which determine adaptive and pathological reactions in developing fetus. Regulation of metabolic relationships is a necessary part of systemogenesis and after development of the definitive cells and functional systems blocks the correlative systems. This mechanism is very important for development of the regulatory systems of the fetus forming postnatal homeostasis.
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