[Comparison of immunochemical and biochemical methods for determination of occult fecal blood].

Cas Lek Cesk

Interní odd. fakult. polikliniky fakultní nemocnice, Praha.

Published: March 1992

AI Article Synopsis

  • The study compared two tests for detecting occult fecal blood loss in patients undergoing endoscopic procedures: the Hemolex test and the Haemoccult test.
  • The Hemolex test demonstrated a higher sensitivity (48.6%) compared to the Haemoccult test (17.1%), while specificity was slightly lower for Hemolex (90%) versus Haemoccult (100%).
  • The findings suggest that the immunochemical Hemolex test may offer advantages in detecting occult blood loss, indicating its potential for broader clinical application.

Article Abstract

The authors compared two tests of occult Fecal Blood Loss--the immunochemical Hemolex test based on agglutination of latex particles lined with antibodies against human haemoglobin and the biochemical Haemoccult test. Both tests were used to examine 55 patients invited to the department for endoscopic polypectomy or coloscopy as part of dispensarization after resection of colorectal carcinoma. The sensitivity of the Hemolex test (48.6%) is statistically significantly higher, as compared with the Haemoccult test (17.1%), the specificity is insignificantly lower in the Hemolex test (90%), as compared with the Haemoccult test (100%). The results indicate some advantages of the immunochemical examination of occult Fecal Blood Loss and the assumed area of its application.

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