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Nucleation-Supersaturation Dual-Drive Crystallization Strategy Enables Efficient Protein Crystallization.
Small
May 2024
State Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai, 200237, China.
A rational crystallization strategy is essential to obtain high-quality protein crystals, yet the established methods suffer from different limitations arising from the single regulation on either nucleation or supersaturation. Herein, a nucleation-supersaturation dual-driven crystallization (DDC) strategy that realizes synergistic regulation of heterogeneous nucleation sites and solution supersaturation based on dual surface and confinement effects for efficient protein crystallization is reported. This strategy relies on a p(PEGDA-co-DMAA) hydrogel template with pre-filled NaCl under designed concentrations.
View Article and Find Full Text PDFPotential health risks of foodborne performance-enhancing drugs in competitive sports.
Heliyon
October 2023
College of Sport of Southwest Forestry University, Kunming, 650224, China.
Athletes need to consume a significant amount of energy during prolonged training and in high-intensity competition. It is necessary for them to take nutritional foods that recharge their bodies. However, in sporting events of recent years, both domestic and international, many positive drug tests are found to be caused by the ingestion of foods that contain performance-enhancing drugs (PEDs).
View Article and Find Full Text PDFEffectiveness of hallux valgus surgery on improving health-related quality of life: A follow up study.
Foot Ankle Surg
June 2022
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain; Faculty of Nursing, Universidad de Castilla-La Mancha, Albacete, Spain.
Background: Hallux valgus (HV) negatively impacts health-related quality of life (HRQoL). Patientreported outcome measures (PROMs) are increasingly used in clinical studies of the foot and ankle. We aimed to evaluate the effect of HV surgery on PROMs (i.
View Article and Find Full Text PDFHallux valgus associated to osteoarthritis: Clinical-radiological outcomes of modified SERI technique at mid- to long-term follow-up. A retrospective analysis.
Foot Ankle Surg
January 2022
II Clinic of Orthopaedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Introduction: Treatment of hallux valgus deformity associated with mild or moderate osteoarthritis (OA) is still a topic of debate. In the literature, there are few studies concerning the management of patients affected by this condition. This study aims to report the experience at mid- to long-term results of an original joint-preserving surgical technique.
View Article and Find Full Text PDFRadiological evaluation of the Stoffella metatarsal I osteotomy in the treatment of hallux valgus.
Pol Merkur Lekarski
March 2019
Sub-Department of Orthopedics, Department of Neuroorthopedics, Mazovian Centre of Rehabilitation STOCER, Konstancin-Jeziorna, Poland.
Unlabelled: The Stoffella surgical method is a reverse Chevron distal metatarsal osteotomy, typically used in younger patients, with good bone quality. The technique is suitable for a variety of cases, from mild to severe, since the head of the first metatarsal may be moved laterally to the edge of the first metatarsal bone, thereby allowing for a significant degree of correction.
Aim: The aim of the paper is to review the radiological results of patients suffering from hallux valgus who underwent Stoffella metatarsal I osteotomy.
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