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Factitious Cushing's syndrome, hypopituitarism, and self-provoked skin lesions: when the skin mirrors the soul.
Endocrinol Diabetes Metab Case Rep
August 2021
Unit of Dermatology of Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Summary: Factitious Cushing's syndrome (CS) is a very rare form of Münchausen syndrome. Its presentation and course are extremely heterogeneous, and diagnosis is generally challenging. We report the case of a 52-year-old woman who was initially investigated because of the occurrence of cushingoid features.
View Article and Find Full Text PDFAlcohol Consumption as a Causator and/or an Accelerator of Neuropathy in People With Diabetes Is Regularly Overlooked.
Diabetes Ther
October 2021
Grandview Endocrinology, Grandview Medical Group, 3525 Independence Dr, Homewood, AL, 35209, USA.
Patients with diabetes and distal symmetrical polyneuropathy (DSP) are routinely evaluated for etiologies other than diabetes, including vitamin B12 deficiency, paraproteinemia, hypothyroidism and drug or autoimmune-induced neuropathy. However, the most common cause of DSP, next to that of diabetes, is alcohol intake, which is almost never evaluated. In addition to assessment of alcohol intake based on patient history, which often leads to an underestimation of alchohol intake, markers of a high alcohol intake (elevated liver enzymes, uric acid, triglycerides, low magnesium or low folic acid levels) should be obtained.
View Article and Find Full Text PDFPatient Preparation for Outpatient Blood Work and the Impact of Surreptitious Fasting on Diagnoses of Diabetes and Prediabetes.
Mayo Clin Proc Innov Qual Outcomes
August 2020
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Objective: To describe patient preparation for routine outpatient blood work and examine the implications of surreptitious fasting on interpretation of glucose results.
Patients And Methods: We designed a survey and administered it between September 1, 2016, and April 30, 2017, to assess fasting behaviors in a convenience sample of 526 adults presenting for outpatient blood work in 2 health systems between 7 am and 12 pm. We reviewed the electronic health records to extract glucose results.
Integrating patient-centric indications into the prescribing process: Experience at a tertiary academic medical center.
Am J Health Syst Pharm
May 2020
Department of Pharmacy, VA Palo Alto Health Care System, Palo Alto, CA.
Purpose: To describe the development of and implementation of a patient-centric clinical indications library (CIL) into the prescribing process and determine the operational and humanistic outcomes (from prescriber, pharmacist, and patient perspectives) of including indications on outpatient prescription labels.
Methods: A descriptive retrospective data analysis was conducted. Multiple stakeholder groups were engaged to develop and integrate the CIL into the prescription package.
Lab-on-a-screen-printed electrochemical cell for drop-volume voltammetric screening of flunitrazepam in untreated, undiluted alcoholic and soft drinks.
Biosens Bioelectron
May 2019
Department of Chemistry, University of Ioannina (UOI), Ioannina 45110, Greece. Electronic address:
Flunitrazepam, also known as "Rohypnol" or "Rophy" among other trade and street names, is an extremely potent benzodiazepine that is prescribed to treat severe insomnia. Due to these attributes, flunitrazepam, when is surreptitiously administered to an alcoholic or soft drink, is associated with "drug-facilitated sexual assault". We report here for the first time, a low cost lab-on-a-screen-printed electrochemical cell (SPC) based on iron-sparked graphite working electrode modified with glucose oxidase (GOx) and glucose hydrogel droplets (GluHD) for the detection of flunitrazepam.
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