Diagnosis and management of adenocarcinoma of the ampulla of Vater during pregnancy.

Eur J Obstet Gynecol Reprod Biol

Department of Digestive Surgery, Service Pr Gamerre, Hospital La Conception, 147 Boulevard Baille, 13385 Marseille Cedex, France.

Published: April 2005

Background: Cancer of the biliary tract has a poor prognosis and its association with pregnancy is uncommon. Early diagnosis allowing curative surgical resection offers the only hope of long-term survival.

Case: This report describes the case of a young 26-week-pregnant woman admitted for cholestatis documented by clinical and laboratory examination. Ultrasonography (US) and magnetic resonance cholangiopancreatography (MRCP) were indicative of common bile tract obstruction. Caesarian section was performed at 32 weeks of pregnancy and the tumor was promptly biopsied. Histology demonstrated carcinoma of the ampulla of Vater. The patient underwent a Whipple procedure. Both mother and baby survived.

Conclusion: Pregnant patients with digestive cancer require careful management. Acute non-invasive assessment and radical surgery improve outcome for both the mother and fetus.

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http://dx.doi.org/10.1016/j.ejogrb.2004.01.048DOI Listing

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