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Baicalein inhibits PRRSV through direct binding, targeting EGFR, and enhancing immune response.
Vet Res
January 2025
Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Porcine reproductive and respiratory syndrome virus (PRRSV) presents significant economic challenges to the global pork industry due to its ability to mutate rapidly. The current commercial vaccines have limited effectiveness, and there are strict restrictions on the use of antiviral chemical drugs. Therefore, it is urgent to identify new strategies for preventing and controlling PRRSV infections.
View Article and Find Full Text PDFCharacteristics identification and mitigating potentials of provincial gaseous reactive nitrogen emissions from livestock and poultry breeding systems in China.
J Environ Manage
January 2025
College of Environmental Science and Engineering, Key Laboratory of Beijing on Regional Air Pollution Control, Beijing University of Technology, Beijing, 100124, China.
The growth of population and changes in dietary structure have led to a continuous increase in demand for livestock and poultry products, resulting in the increase of the gaseous reactive nitrogen (GNr) emissions from livestock and poultry breeding systems and posing a threat to the human and ecosystem health. The characteristics from GNr emissions of six livestock and poultry breeding systems at the provincial level of China in 2020 were evaluated with the framework of life cycle analysis. Additionally, this study explored the impact of silage maize replacing traditional maize as feed on reducing GNr emissions.
View Article and Find Full Text PDFSingle-Nucleus RNA Sequencing Reveals Cellular Transcriptome Features at Different Growth Stages in Porcine Skeletal Muscle.
Cells
January 2025
Chongqing Academy of Animal Science, Chongqing 402460, China.
Porcine latissimus dorsi muscle (LDM) is a crucial source of pork products. Meat quality indicators, such as the proportion of muscle fibers and intramuscular fat (IMF) deposition, vary during the growth and development of pigs. Numerous studies have highlighted the heterogeneous nature of skeletal muscle, with phenotypic differences reflecting variations in cellular composition and transcriptional profiles.
View Article and Find Full Text PDFModified multiplex PCR for serotyping and pathotyping of .
J Med Microbiol
January 2025
Faculty of Public Health, Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon 47000, Thailand.
is a zoonotic pathogen that causes invasive infections in humans who have been in close contact with infected pigs or contaminated pork-derived products. There is currently no consensus on the universal virulence factors or markers that can differentiate pathogenic from non-pathogenic or commensal isolates. A diagnostic tool for serotyping and pathotyping of is required for active public health surveillance and the One-Health approach.
View Article and Find Full Text PDFIsolation and Detection of the Emerging Pathogen in Clinical Stool Samples and the Potential Transmission by Meat Samples in Retail.
Microorganisms
November 2024
Department of Veterinary and Biosciences, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
The significance of as a foodborne pathogen is increasingly acknowledged, but the assessment of its occurrence and transmission remains challenging due to the lack of validation of selective isolation, detection, and identification methods. The aim of the present study was to examine its presence on various meat samples at the retail level in order to assess a potential foodborne transmission and its occurrence in clinical stool samples. First, the evaluation and selection of a selective enrichment broth and isolation medium, combined with an optimized identification by MALDI-TOF MS, as well as a suitable DNA extraction method and a PCR-based detection strategy were developed.
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