The economic impact of parkinsonism has been getting more significant due to the increasing prevalence of Parkinson's disease and the modern therapies available nowadays. The present study is supposed to update the existing databases and to provide a sound foundation for rational decision-making in the health care sector. It does not only focus on the direct costs of this disease incurred by 75 patients over a longer period, but also and for the first time, takes a look on the indirect cost as well. The study shows that the expenses for PD-related house rebuilding and early retirement make up for a substantial share among the indirect costs. In the overall analysis, the ratio between both, direct and indirect costs appear to be relatively balanced with slight domination of the direct costs.
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http://dx.doi.org/10.1055/s-2004-830106 | DOI Listing |
ACS Energy Lett
January 2025
George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
The global lithium-ion battery recycling capacity needs to increase by a factor of 50 in the next decade to meet the projected adoption of electric vehicles. During this expansion of recycling capacity, it is unclear which technologies are most appropriate to reduce costs and environmental impacts. Here, we describe the current and future recycling capacity situation and summarize methods for quantifying costs and environmental impacts of battery recycling methods with a focus on cathode active materials.
View Article and Find Full Text PDFAm J Primatol
January 2025
Primate Behavioral Ecology Lab, Instituto de Neuro-etología, Universidad Veracruzana, Xalapa, México.
Parasitism, a widespread nutrient acquisition strategy among animals, results from a long evolutionary history where one species derives its metabolic needs from another. Parasites can significantly reduce host fitness, affecting reproduction, growth, and survivability. Vertebrate hosts exhibit defensive strategies against parasites, including "sickness behaviors" such as lethargy and self-grooming to remove ectoparasites.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Department of Orthopaedics, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
Background: Patellofemoral pain (PFP) is a common musculoskeletal disorder resulting in anterior knee pain. Physiotherapy is the current standard treatment, while surgical intervention (tibial tubercle transfer [TTT]) is reserved for chronic cases when nonoperative treatment has failed. TTT can result in clinically meaningful improvement in patients with patellofemoral maltracking without instability.
View Article and Find Full Text PDFCurr Biol
January 2025
Norwegian Institute for Nature Research (NINA), Trondheim 7034, Norway.
Understanding the movements of highly mobile animals is challenging because of the many factors they must consider in their decision-making. Many seabirds, for example, are adapted to use winds to travel long distances at low energetic cost but also potentially benefit from targeting specific foraging hotspots. To investigate how an animal makes foraging decisions, given the inevitable trade-off between these factors, we tracked over 600 foraging trips of breeding Manx shearwaters (Puffinus puffinus; N = 218 individuals) using GPS accelerometers.
View Article and Find Full Text PDFJ Bone Joint Surg Am
November 2024
Department of Orthopaedic Surgery, Harvard Medical School, Boston Shoulder Institute, Massachusetts General Hospital, Boston, Massachusetts.
Background: Rotator cuff repair (RCR) is a frequently performed outpatient orthopaedic surgery, with substantial financial implications for health-care systems. Time-driven activity-based costing (TDABC) is a method for nuanced cost analysis and is a valuable tool for strategic health-care decision-making. The aim of this study was to apply the TDABC methodology to RCR procedures to identify specific avenues to optimize cost-efficiency within the health-care system in 2 critical areas: (1) the reduction of variability in the episode duration, and (2) the standardization of suture anchor acquisition costs.
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