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[Malignant melanoma of the choroid associated with neurofibromatosis].
J Fr Ophtalmol
June 1993
Service d'Ophtalmologie, C.H.R.U., Hôpital Gabriel Montpied, Clermont-Ferrand.
A sixteen-year-old white girl with peripheral neurofibromatosis (NF1), who had been treated for a glioma of the optic nerves and chiasma developed a choroidal mass in her only functional eye. After a transchoroïdal biopsy, the pathologic examination disclosed a choroïdal melanoma of epithelioid cell type, using morphological criteria as well as an immunohistochemical study. After treatment with a ruthenium plaque, the tumor completely regressed over 4 months.
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