Purpose: To report the value of endoretinal biopsy in establishing the diagnosis of severe posterior uveitis.
Methods: A clinicopathologic report of three patients with severe posterior uveitis unresponsive to corticosteroids and with a negative systemic workup. These patients subsequently underwent vitrectomy and endoretinal biopsy.
Results: Endoretinal biopsy provided an accurate diagnosis in the three cases, leading to appropriate treatment. Histopathologic examination of the three retinal samples confirmed the diagnosis of sarcoidosis, tuberculosis, and lymphoma. Targeted treatment improved the ocular conditions in all three cases.
Conclusions: In selected cases of severe bilateral vision-threatening uveitis, retinal biopsy may be indicated as a last resort to confirm a suspected diagnosis of infectious disease or malignancy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09273940590909149 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Endoretinal biopsy outcomes in suspected vitreoretinal lymphoma after inconclusive vitreous cytology.
J Fr Ophtalmol
December 2024
Department of Ophthalmology, Hospital Clínic of Barcelona, University of Barcelona, Sabino Arana, 1, 08028 Barcelona, Spain.
Objective: To review the clinical utility of endoretinal biopsies in diagnostically undefined cases of vitreoretinal lymphoma (VRL) with negative vitreous cytology.
Methods: Retrospective case series including all consecutive patients who underwent endoretinal biopsies in a tertiary care center, Hospital Clinic of Barcelona (Spain), between 2014 and 2020.
Results: A total of 5 patients were included in this study.
Endoretinal biopsy in establishing the diagnosis of uveitis: a clinicopathologic report of three cases.
Ocul Immunol Inflamm
February 2005
Department of Ophthalmology, Pitié-Salpêtrière Hospital Paris France.
Purpose: To report the value of endoretinal biopsy in establishing the diagnosis of severe posterior uveitis.
Methods: A clinicopathologic report of three patients with severe posterior uveitis unresponsive to corticosteroids and with a negative systemic workup. These patients subsequently underwent vitrectomy and endoretinal biopsy.
Clinicopathologic correlations in acute retinal necrosis caused by herpes simplex virus type 2.
Arch Ophthalmol
November 1996
Department of Ophthalmology, University of California, San Diego School of Medicine, La Jolla, USA.
The acute retinal necrosis syndrome is a rapidly progressive and potentially devastating disease. A case of acute retinal necrosis developed in an immunocompetent man, Presumably due to the stress, trauma, or immunomodulation related to a craniotomy for a parasellar craniopharyngioma. Vitrectomy and endoretinal biopsy were performed.
View Article and Find Full Text PDFClinicopathologic study of retinal and choroidal biopsies in intraocular inflammation.
Am J Ophthalmol
May 1995
Doheny Eye Institute, Los Angeles, CA 90033, USA.
Purpose: We reviewed the clinical and histopathologic features of 33 intraocular tissue biopsy specimens from 32 patients and assessed the value of retinal and chorioretinal biopsies performed in patients with intraocular inflammation.
Methods: Twenty-four endoretinal biopsies and nine chorioretinal or choroidal biopsies were performed. On the basis of clinical indications, the specimens were processed for light microscopy, electron microscopy, immunohistochemical staining, in situ DNA hybridization, and polymerase chain reaction.
Central nervous system herpesvirus infection in systemic lupus erythematosus: diagnosis by endoretinal biopsy.
J Rheumatol
June 1993
Section of Rheumatology, Washington Hospital Center, Washington, DC 20010.
A 31-year-old woman with systemic lupus erythematosus (SLE) developed meningoencephalitis, followed by transverse myelitis. The clinical picture was otherwise not consistent with a lupus flare. Extensive diagnostic evaluation was unrevealing.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!