The aim was to study secular changes in head dimensions of Japanese adult males. The subjects were all of Japanese birth and Japanese ancestry. The age range of the subjects was between 18 and 25 years. Four head measurements were taken: head length, head breadth, head height and head circumference. In addition, stature and body weight were also measured. All measurements were made by one observer (Fumio Ohtsuki) from 1998 to 2001. The present sample was compared with the series taken between 1910 and 1917 of Matsumura (J Fak Sci Imp Univ Tokyo Sec 1 (1925) 1) and the one measured in 1965 of Morita and Ohtsuki (Hum Biol 45 (1973) 151). The present study demonstrated the presence of larger means for head length, head breadth and cephalic index in the current sample than in their predecessors of about 35-85 years ago. Also, the present series displayed larger head circumference than that of the Morita and Ohtsuki series. Using ANOVA, head length and head breath showed significant (p<0.01) differences among all birth-year cohorts from 1978 to 1983 of the current sample. Head height, head circumference and cephalic index did not display significant differences. However, the slope of the regression line indicated that all measurements as well as the cephalic index showed slightly decreasing tendencies during the investigated period. These results suggest that brachycephalization has been occurring for approximately about 35-85 years in adult Japanese males, but the change seems to have become reversed slightly during the period covered by the present sample.
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http://dx.doi.org/10.1016/j.jchb.2003.04.001 | DOI Listing |
Oncol Ther
January 2025
Coordinator of the International Head and Neck Scientific Group, Padua, Italy.
Introduction: Laryngeal chondrosarcoma (CS) is a rare indolent malignant tumor. High-grade (G3), dedifferentiated (DD), and myxoid (MY) CSs are considered more aggressive subtypes due to their metastatic potential and relatively poor outcomes. The aim of this systematic review is to evaluate treatment modalities and survival outcomes in patients affected by these rarer CS subtypes.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Dentistry Department, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Objective: To compare the treatment of osteoradionecrosis (ORN) using a protocol that incorporates antimicrobial photodynamic therapy with a conventional treatment protocol.
Methodology: This retrospective study analyzed 55 patients diagnosed with ORN at a reference hospital between 2002 and 2021. Patients were treated using two different clinical protocols.
Hum Genet
January 2025
Division of Hearing and Balance Research, National Institute of Sensory Organs, NHO Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-Ku, Tokyo, 152-8902, Japan.
There are hundreds of rare syndromic diseases involving hearing loss, many of which are not targeted for clinical genetic testing. We systematically explored the genetic causes of undiagnosed syndromic hearing loss using a combination of whole exome sequencing (WES) and a phenotype similarity search system called PubCaseFinder. Fifty-five families with syndromic hearing loss of unknown cause were analyzed using WES after prescreening of several deafness genes depending on patient clinical features.
View Article and Find Full Text PDFArch Dermatol Res
January 2025
Tianjin Medical University, Tianjin, 300102, China.
Objective: This study aims to investigate the genetic link between psoriasis and sudden sensorineural hearing loss (SSNHL).
Methods: From a genetic standpoint, this study further highlighted the connection between psoriasis and SSNHL. Single nucleotide polymorphisms (SNPs) connected to SSNHL could be found using a genome-wide association study from the IEU OpenGWAS project website.
Eye (Lond)
January 2025
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Objectives: To use finite element (FE) modeling and in vivo optical coherence tomography (OCT) imaging to explore the effect of ciliary muscle traction on optic nerve head (ONH) deformation during accommodation.
Methods: We developed a FE model to mimic the ciliary muscle traction during accommodation, and varied the stiffness of the sclera, choroid, Bruch's membrane (BM), prelaminar neural tissue and lamina cribrosa (LC) to assess their effects on accommodation-induced ONH strains. To validate the FE model, OCT images of the right eyes' ONHs from 20 subjects (25 ± 1.
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