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The Novel Role of GDI2: A Mini-Review.
Ann Med Med Res
August 2024
Department of Pediatrics, Children's Foundation Research Institute at Le Bonheur Children's Hospital, University of Tennessee Health Science Center, USA.
GDP Dissociation Inhibitor 2 (GDI2) plays a crucial role in maintaining cellular homeostasis by regulating Rab GTPases involved in vesicular transport. This review highlights the importance of GDI2 in various biological processes, particularly embryonic development, apoptosis regulation, cancer, and immune responses. GDI2's essential function in embryonic development is evidenced by the embryonic lethality observed in GDI2 knockout mice.
View Article and Find Full Text PDFAnalyzing Geospatial and Socioeconomic Disparities in Breast Cancer Screening Among Populations in the United States: Machine Learning Approach.
JMIR Cancer
January 2025
Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN, 38103, United States, 1 9012875836.
Background: Breast cancer screening plays a pivotal role in early detection and subsequent effective management of the disease, impacting patient outcomes and survival rates.
Objective: This study aims to assess breast cancer screening rates nationwide in the United States and investigate the impact of social determinants of health on these screening rates.
Methods: Data on mammography screening at the census tract level for 2018 and 2020 were collected from the Behavioral Risk Factor Surveillance System.
Nanosecond Nanothermometry in an Electron Microscope.
Nano Lett
January 2025
University Paris-Saclay, CNRS, Laboratoire de Physique des Solides, Orsay 91405, France.
Thermal transport in nanostructures plays a critical role in modern technologies. As devices shrink, techniques that can measure thermal properties at nanometer and nanosecond scales are increasingly needed to capture transient, out-of-equilibrium phenomena. We present a novel pump-probe photon-electron method within a scanning transmission electron microscope (STEM) to map temperature dynamics with unprecedented spatial and temporal resolutions.
View Article and Find Full Text PDFPositive clinical tests for medial epicondylalgia are more common than tests for lateral epicondylalgia in recreational pickleball players: A cross-sectional study.
J Hand Ther
January 2025
Department of Physical Therapy, University of Tennessee at Chattanooga, Chattanooga, TN. Electronic address:
Background: Epicondylalgia is a common overuse injury in tennis. However, little is known regarding epicondylalgia in pickleball.
Purpose: This study examined the prevalence of positive epicondylalgia tests in recreational pickleball players and the relationship between positive tests and player characteristics.
Frequencies and functions of vocalizations and gestures in the second year of life.
PLoS One
January 2025
Origin of Language Laboratories, School of Communication Sciences and Disorders, University of Memphis, Memphis, Tennessee, United States of America.
Speculations on the evolution of language have invoked comparisons across human and non-human primate communication. While there is widespread support for the claim that gesture plays a central, perhaps a predominant role in early language development and that gesture played the foundational role in language evolution, much empirical information does not accord with the gestural claims. The present study follows up on our prior work that challenged the gestural theory of language development with longitudinal data showing early speech-like vocalizations occurred more than 5 times as often as gestures in the first year of life.
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