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Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate.

Microbiology (Reading)

January 2025

School of Life and Environmental Sciences, The University of Sydney, Camperdown, New South Wales, Australia.

Most Gram-negative bacteria synthesize a plethora of cell surface polysaccharides that play key roles in immune evasion, cell envelope structural integrity and host-pathogen interactions. In the predominant polysaccharide Wzx/Wzy-dependent pathway, synthesis is divided between the cytoplasmic and periplasmic faces of the membrane. Initially, an oligosaccharide composed of 3-8 sugars is synthesized on a membrane-embedded lipid carrier, undecaprenyl pyrophosphate, within the cytoplasmic face of the membrane.

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Background: Black adults in the United States experience disproportionately high rates of tobacco- and obesity-related diseases, driven in part by disparities in smoking cessation and physical activity. Smartphone-based interventions with financial incentives offer a scalable solution to address these health disparities.

Objective: This study aims to assess the feasibility and preliminary efficacy of a mobile health intervention that provides financial incentives for smoking cessation and physical activity among Black adults.

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Background: Systemic lupus erythematosus (SLE) is characterized by a range of symptoms that often cluster together, impacting the quality of life (QoL) of affected individuals.

Objective: To delineate the composition of symptom clusters in patients with SLE and analyze their correlation with QoL, thus providing a basis for symptom management.

Methods: Using convenience sampling, 201 patients were recruited.

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This study explored the structure and temporal evolution of the relationship among depression, maladaptive cognition, and internet addiction (DMI) among university students by focusing on topological and dynamic properties in a network analysis. A 3-year longitudinal survey was conducted with 873 university students (M = 18.32, SD = 0.

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is a medicinal plant native to East Asia with its diverse therapeutic potentials. In particular, the antioxidant effect of this plant is well known, but there has been little research on the antioxidant effect according to different habitats or ages. In this study, we evaluated the proximate composition, mineral, saponin, rutin, total phenolic and flavonoid contents, and antioxidant activities of leaf extracts of plants cultivated from two different regions (New Zealand and Jeju Island, Korea) and of the same age (2-year-old plants).

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