The inflammation of the arachnoid mater may produce a fibrinous exudate around the roots that causes them to adhere to the dural sheath. We report the case of a man aged 23 years who suffered from acute inflammatory truncated sciatica. The diagnosis of adhesive arachnoiditis was made in front of clinical arguments associated to typical signs on Myelo CT Scan and MRI. The only explanation ever found was a traumatic lumbar puncture at the age of 6 years for suspected meningitis. Sequelae of arachnoiditis are difficult to diagnosis. When MRI or myelography suggests it as a possibility, precise directed questioning is necessary to seek a history, albeit distant, of spinal or meningeal events.
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http://dx.doi.org/10.1016/j.jbspin.2004.03.013 | DOI Listing |
J Tradit Complement Med
November 2024
Department of Pharmacology, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Chengalpattu, Tamil Nadu, India.
Background: Luteolin, a natural flavonoid, exhibits antioxidant and anti-inflammatory properties and has been investigated for potential health benefits. Its focus on migraine management arises from its ability to mitigate neuroinflammation, a key factor in migraine attacks.
Methods: pkCSM and Swiss ADME were employed to assess luteolin's pharmacokinetic properties, revealing challenges such as low water solubility and limited skin permeability.
Comput Struct Biotechnol J
December 2024
Department of Orthopaedic Surgery, University of Regensburg, Asklepios Klinikum, Bad Abbach, Germany.
Background: Large Language Models (LLMs) such as ChatGPT are gaining attention for their potential applications in healthcare. This study aimed to evaluate the diagnostic sensitivity of various LLMs in detecting hip or knee osteoarthritis (OA) using only patient-reported data collected via a structured questionnaire, without prior medical consultation.
Methods: A prospective observational study was conducted at an orthopaedic outpatient clinic specialized in hip and knee OA treatment.
EXCLI J
November 2024
Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.
Since the outbreak of the COVID-19 pandemic, there has been a global surge in patients presenting with prolonged or late-onset debilitating sequelae of SARS-CoV-2 infection, colloquially termed long COVID. This narrative review provides an updated synthesis of the latest evidence on the neurological manifestations of long COVID, discussing its clinical phenotypes, underlying pathophysiology, while also presenting the current state of diagnostic and therapeutic approaches. Approximately one-third of COVID-19 survivors experience prolonged neurological sequelae that persist for at least 12-months post-infection, adversely affecting patients' quality of life.
View Article and Find Full Text PDFJ Sci Teacher Educ
August 2024
Institute for Language Sciences, Utrecht University, Utrecht, The Netherlands.
Integrated science-and-literacy programs have proven to positively affect both language proficiency and science knowledge. Because making connections is important in both text comprehension and understanding the disciplinary core ideas taught in science, it seems worthwhile to explore the potential of integrating text structure instruction in science education. Therefore, we conducted a design-based research (DBR) in collaboration with teachers in the upper levels of primary education in the Netherlands.
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