Background: The aim of this study was to evaluate the relationship between the duration of arousal and the type, duration and minSaO(2) of apneas/hypopneas, and the time of night and sleep stage when they occurred.
Material/methods: We measured the duration of arousals associated with apneas (A) and hypopneas (H) in 10 polysomnographic recording. Arousals were categorized as: 1) Short Electroencephalographic Arousal (SEA: 3-15 s) and 2) Awakenings (>15 s). The dependent variable for multiple logistic regression analysis was duration of arousal (0 = 3-11 s, 1 = >11 s); the independent variables were event (0 = H, 1 = A), event duration (0 = 10-20 s, 1 = >20 s), sleep stage (0 = REM, 1 = NREM 1-2); minSaO(2) (0 = 86%, 1 = <86%) and time of night (0 = at or before 3:00 AM, 1 = after 3:00 AM).
Results: We analyzed 1536 apneas and hypopneas. 80.3% had arousal, 61% SEA and 19.3% awakenings. The median duration of arousal was higher in apneas (A: 12 s, H: 9.2 s, p<0.001). The apneas and events >20 s with a minSaO(2) <86% had a higher probability of arousal >11 s (apnea: OR 2.1, p<0.001; events >20 s: OR 1.5, p<0.01; minSaO(2) <86%: OR 1.4, p<0.05).
Conclusions: Arousals were greater in apneas than in hypopneas. Apneas and events >20 s with a minSaO(2) <86% were associated more frequently with arousal >11 s.
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Int J Behav Med
January 2025
Department of Stomatology, Zhejiang Hospital, Hangzhou, China.
Background: Dental caries (DC) is a significant common disease of the oral cavity. Recently, researchers have focused more on the impact of poor sleep habits on the incidence and development of DC, which aroused our interest in the study of the correlation and causal relationship between sleep and dental caries.
Methods: In this study, Linkage disequilibrium score (LDSC) regression method was used to found the genetic correlation between different sleep traits and DC, while bidirectional Mendelian randomization (MR) methods were used to explore the causal relationship.
Handb Clin Neurol
January 2025
Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland; Research Cluster Molecular and Cognitive Neurosciences, University of Basel, Basel, Switzerland; Department of Biomedicine, University of Basel, Basel, Switzerland.
The nonvisual effects of light in humans are mainly conveyed by a subset of retinal ganglion cells that contain the pigment melanopsin which renders them intrinsically photosensitive (= intrinsically photosensitive retinal ganglion cells, ipRGCs). They have direct connections to the main circadian clock in the suprachiasmatic nuclei (SCN) of the hypothalamus and modulate a variety of physiological processes, pineal melatonin secretion, autonomic functions, cognitive processes such as attention, and behavior, including sleep and wakefulness. This is because efferent projections from the SCN reach other hypothalamic nuclei, the pineal gland, thalamus, basal forebrain, and the brainstem.
View Article and Find Full Text PDFClin Neurophysiol
January 2025
Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address:
Objective: Sleep-related hypermotor epilepsy (SHE) is a relatively uncommon epilepsy syndrome, characterized by seizures closely related to the sleep cycle. This study aims to explore interictal electroencephalographic (EEG) characteristics in SHE.
Methods: We compared EEG data from 20 patients with SHE, 20 patients with focal epilepsy (FE), and 14 healthy controls, carefully matched for age, sex, education level, epilepsy duration, and drug-resistant epilepsy.
J Neurosurg
January 2025
Departments of1Biomedical Engineering.
Objective: Epilepsy is a common neurological disease affecting nearly 1% of the global population, and temporal lobe epilepsy (TLE) is the most common type. Patients experience recurrent seizures and chronic cognitive deficits that can impact their quality of life, ability to work, and independence. These cognitive deficits often extend beyond the temporal lobe and are not well understood.
View Article and Find Full Text PDFJ Funct Morphol Kinesiol
January 2025
Department of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.
Time estimation was investigated in 24 healthy adults, including 12 women and 12 men, before and after an exhaustive exercise. : We compared the ability of estimating time intervals in the range 1 to 5 s using tasks requiring mental counting and tasks that did not allow it. Time estimation and blood lactate levels were evaluated before and at the end of the exercise.
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