The pharmacokinetics of tigecycline, when given as a 100-mg loading dose followed by 50 mg every 12 h, were determined in serum and blister fluid. The peak tigecycline concentration and half-life in serum were greater than those in blister fluid. Tigecycline penetrates into blister fluid well, with a mean penetration rate of 74%.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1068611 | PMC |
| http://dx.doi.org/10.1128/AAC.49.4.1629-1632.2005 | DOI Listing |
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