Background: Cyclical Vomiting Syndrome (CVS) is characterised by discrete, unexplained episodes of intense nausea and vomiting, and mainly affects children and adolescents. Comprehending Cyclical Vomiting Syndrome requires awareness of the severity of nausea experienced by patients. As a subjective symptom, nausea is easily overlooked, yet is the most distressing symptom for patients and causes many behavioural changes during attacks.
Case Presentation: This first-hand account of one patient's experience of Cyclical Vomiting Syndrome shows how severe nausea contributed to the development of anticipatory nausea and vomiting (ANV), a conditioned response frequently observed in chemotherapy patients. This conditioning apparently worsened the course of the patient's disease. Anticipatory nausea and vomiting has not previously been recognised in Cyclical Vomiting Syndrome, however predictors of its occurrence in oncology patients indicate that it could complicate many cases.
Conclusion: We suggest a model whereby untreated severe and prolonged nausea provokes anxiety about further cyclical vomiting attacks. This anxiety facilitates conditioning, thus increasing the range of triggers in a self-perpetuating manner. Effective management of the nausea-anxiety feedback loop can reduce the likelihood of anticipatory nausea and vomiting developing in other patients.
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| http://dx.doi.org/10.1186/1471-2431-5-3 | DOI Listing |
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Article Synopsis
- Cyclic vomiting syndrome (CVS) is a disorder that causes recurrent severe nausea and vomiting, often leading to missed diagnoses and high healthcare costs, with research primarily focused in regions like the US.
- The purpose of this review is to evaluate the prevalence and incidence of CVS worldwide, highlighting gaps in current knowledge and the need for increased awareness and collaboration.
- It emphasizes the importance of addressing disparities in health outcomes, particularly for African Americans and Hispanics in the US, to improve targeted interventions and achieve equitable healthcare globally.
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