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Comprehensive Digital Documentation of Teratology studies.
Reprod Toxicol
January 2025
NEXTREAT Laboratories, Hajmáskér, Hungary.
One of the main endpoints for the evaluation of Developmental and Reproductive Toxicology (DART) studies is the determination of potential effects of a test substance on the skeleton during foetal development. In the course of a DART study according to the OECD 414 guideline, 400 to 500 gestational day 20-old (GD20), alizarin red and alcian blue-stained (ARAB) rat foetuses have to be assessed by a teratology expert, which is a time consuming and sub-optimally documented process. We have developed a method which allows for a standardised, comprehensive, quick and easy to perform, head-to-toe digital documentation of ARAB-stained GD20 rat foetuses.
View Article and Find Full Text PDFA Combination of Conventional Transconjunctival Lower Blepharoplasty and Percutaneous Nanofat Grafting in a Young Chinese Population With Eyelid Bags and Tear Trough Deformities.
J Cosmet Dermatol
January 2025
Department of Dermatology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.
Objective: A simple and minimally invasive combined procedure, including transconjunctival orbital fat removal and transcutaneous resected orbital fat injection, was performed based on the anatomical characteristics of the lower eyelids in our young Chinese patients. Our study aimed to investigate the efficacy and safety of this procedure in our study population.
Methods: In our retrospective study, a total of 183 consecutive patients underwent a combination of traditional transconjunctival blepharoplasty and nanofat grafting between February 2020 and June 2024.
The development of rapid detection techniques for Alexandrium catenella.
Environ Sci Pollut Res Int
January 2025
College of the Environment and Ecology, Xiamen University, Xiamen, 361102, Fujian, People's Republic of China.
Alexandrium catenella is an important toxic algal species in the Alexandrium genus, which can form toxic red tides in large numbers. The paralytic shellfish poisoning (PSP) produced by Alexandrium catenella can seriously endanger human health and threaten the production and development of the aquaculture and fishery industries. Therefore, it is important to explore and develop effective detection and early warning methods for toxic red tides.
View Article and Find Full Text PDFThe PRO-AGE Tool and Its Association With Post Discharge Outcomes in Older Adults Admitted From the Emergency Department.
J Am Geriatr Soc
January 2025
Geriatric Research, Education and Clinical Center, James J. Peters VA Medical Center, Bronx, New York, USA.
Background: Existing risk scores assessing geriatric vulnerability in the emergency department (ED) have shown limited predictive power, especially in diverse populations. We investigated the relationship of a quick and easy-to-administer geriatric vulnerability scoring system with functional decline and mortality in older patients admitted to multiple hospitals through the ED in the United States (US) and Brazil (BR).
Method: Federated, international, multicenter observational study of hospitalized ED patients aged ≥ 65 from US and BR.
The Clinical Efficacy of Extracorporeal Shock Wave Therapy Combined with Platelet Rich Plasma and Exercise for Lateral Epicondylitis: Prospective Randomized Sham-Controlled Ultrasonographic Study.
Arch Phys Med Rehabil
January 2025
Department of Physical Medicine and Rehabilitation, School of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
Objectives: To evaluate the combined effect of two different regenerative therapies, extracorporeal shock wave therapy (ESWT) and platelet-rich plasma (PRP), along with therapeutic exercise, in patients with lateral epicondylitis (LE).
Design: Prospective, Randomized, Sham-Controlled Trial.
Settings: Outpatient clinic.
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