Experimental arthritis in rabbits was induced by M. pneumoniae. We compared it with the arthritis produced by well known animal arthritogenic agents (M. pulmonis and M. arthritidis). Mycoplasmas were detected in the knee joint by different techniques. M. pneumoniae and M. pulmonis produced an acute arthritis that resolved in 2 weeks while, M. arthritidis produced a chronic arthritis. Live M. pneumoniae and M. pulmonis were recovered from the joint during all the experiments. No live M. arthritidis was detected. Live mycoplasmas play an important role in acute arthritis. A similar inflammatory pattern was shown by M. pneumoniae and M. pulmonis. This animal model could be helpful in the study of arthritis induced by a human pathogen mycoplasma.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The response of adipose tissues to Mycoplasma pulmonis and Sendai virus infection in C57BL/6 and DBA/2 mice.
J Vet Med Sci
March 2021
Laboratory of Laboratory Animal Science and Medicine, Department of Applied Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido 060-0818, Japan.
Adipose tissues in mammals are categorized into white and brown adipose tissues in which cellular morphology, cell functions, and tissue distribution are different. White adipose tissue (WAT) plays a major role in energy reservation, while brown adipose tissue (BAT) mainly relates to the thermoregulation of the body. One interesting function of adipose tissue is the response to the infection, especially the pathogens that cause pneumonia.
View Article and Find Full Text PDFHRM analysis as a tool to facilitate identification of bacteria from mussels during storage at 4 °C.
Food Microbiol
February 2020
Lab of Marketing and Technology of Aquatic Products and Foods, Department of Ichthyology and Aquatic Environment, School of Agricultural Sciences, University of Thessaly, Fytokou street, 38446, Volos, Greece.
High-resolution melting (HRM) analysis followed by sequencing was applied for determination of bacteria grown on plates isolated from farmed mussels (Mytilus galloprovincialis) during their storage at 4 °C. The V3-V4 region of the 16S rRNA gene from the isolates was amplified using 16S universal primers. Melting curves (peaks) and high resolution melting curves (shape) of the amplicons and sequencing analysis were used for differentiation and identification of the isolated bacteria, respectively.
View Article and Find Full Text PDFProfiling of cellular immune responses to Mycoplasma pulmonis infection in C57BL/6 and DBA/2 mice.
Infect Genet Evol
September 2019
Laboratory of Laboratory Animal Science and Medicine, Department of Applied Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan. Electronic address:
Mycoplasma infections cause respiratory tract damages and atypical pneumonia, resulting in serious problems in humans and animals worldwide. It is well known that laboratory inbred mouse strains show various susceptibility to Mycoplasma pulmonis (M. pulmonis) infection, which causes murine respiratory mycoplasmosis.
View Article and Find Full Text PDFA Case Report of 2 Sirolimus-Related Deaths Among Infants With Kaposiform Hemangioendotheliomas.
Pediatrics
April 2018
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital and School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Kaposiform hemangioendothelioma (KHE) is a rare infiltrative vascular tumor that is potentially life-threatening when presenting with Kasabach-Merritt phenomenon (KMP). KMP is clinically characterized as severe thrombocytopenia and hypofibrinogenemia and therefore is associated with a high mortality rate. There is no standard of cure for KHE currently.
View Article and Find Full Text PDFClinical, pathological, and molecular investigation of -induced murine respiratory mycoplasmosis in a rat () colony.
Vet World
November 2017
Department of Animal House, School of Biological Sciences, National Institute of Science Education and Research, Bhubaneswar, Odisha, India.
Aim: (MP) remains potentially important rodent pathogen causing murine respiratory mycoplasmosis (MRM) which may go undiagnosed due to its asymptomatic nature. In the present study, we carried out clinical, pathological, and molecular investigations of MP-induced MRM in a rat colony.
Materials And Methods: Two female Wistar rats were observed to be diseased in animal facility of NISER, Bhubaneswar, and were kept in isolation for further investigation.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!