Objectives: To study how body mass index (BMI, kg/m2) at 14 and 31 years (y) changes in BMI between 14 and 31 y, and waist-to-hip ratio (WHR) at 31 y are associated with poor perceived working ability at 31 y.
Design And Subjects: A population-based cohort, originally 11637 people, born in Northern Finland in 1966 was resurveyed at 14 and 31 y.
Measurements: Perceived work ability (measured by modified work ability index, WAI), BMI, WHR, alcohol intake, smoking, basic education and work history were recorded at 31 y and BMI also at 14 y.
Results: Low WAI (15% of lowest values) at 31 y showed a U-shaped association with BMI at 14 y, and also with BMI at 31 y, except in obese males. Low WAI similarly had a U-shaped association with WHR, but in males only, while in females, the probability of low WAI increased almost linearly with WHR. Low WAI was more common among smokers and people with a low level of education. The pattern for alcohol intake was more equivocal, with a nonsignificant finding in males and an almost linear decrease of low WAI with increasing alcohol intake in females.
Conclusions: Work ability, health habits and anthropometric measures should be evaluated regularly in young workers, and preventive measures against diseases leading to premature retirement should be taken in time, for example by the occupational health-care service.
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http://dx.doi.org/10.1038/sj.ijo.0802936 | DOI Listing |
Pathogens
November 2024
The Davies Livestock Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Adelaide, Adelaide, SA 5005, Australia.
, an important cause of enzootic pneumonia in pigs in many countries, has recently been shown to exhibit reduced susceptibility to several antimicrobial classes. In the present study, a total of 185 pig lung tissue samples were collected from abattoirs in Australia, from which 21 isolates of were obtained. The antimicrobial resistance profile of the isolates was determined for 12 antimicrobials using minimum inhibitory concentration (MIC) testing, and a subset ( = 14) underwent whole-genome sequence analysis.
View Article and Find Full Text PDFVet Sci
November 2024
Australian Centre for Antimicrobial Resistance Ecology, Faculty of Sciences, Engineering and Technology, School of Animal and Veterinary Science, The University of Adelaide, Adelaide, SA 5005, Australia.
Antimicrobial resistance (AMR) in , the causative agent of Enzootic Pneumonia in swine, poses a significant challenge to the swine industry. This review focuses on the genetic foundations of AMR in , highlighting the complexity of resistance mechanisms, including mutations, horizontal gene transfer, and adaptive evolutionary processes. Techniques such as Whole Genome Sequencing (WGS) and multiple-locus variable number tandem repeats analysis (MLVA) have provided insights into the genetic diversity and resistance mechanisms of .
View Article and Find Full Text PDFGigascience
January 2024
The Davies Research Centre, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy SA 5371, Australia.
Background: Most DNA methylation studies have used a single reference genome with little attention paid to the bias introduced due to the reference chosen. Reference genome artifacts and genetic variation, including single nucleotide polymorphisms (SNPs) and structural variants (SVs), can lead to differences in methylation sites (CpGs) between individuals of the same species. We analyzed whole-genome bisulfite sequencing data from the fetal liver of Angus (Bos taurus taurus), Brahman (Bos taurus indicus), and reciprocally crossed samples.
View Article and Find Full Text PDFGenes (Basel)
September 2024
Davies Livestock Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Adelaide, SA 5371, Australia.
(1) Background: Target capture sequencing (TCS) is potentially a cost-effective way to detect single-nucleotide polymorphisms (SNPs) and an alternative to SNP array-based genotyping. (2) Methods: We evaluated the effectiveness and reliability of TCS in cattle breeding scenarios using 48 female and 8 male samples. DNA was extracted from blood samples, targeted for 71,746 SNPs with TWIST probes, and sequenced on an MGI platform.
View Article and Find Full Text PDFGigascience
January 2024
The Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA 5371, Australia.
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