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http://dx.doi.org/10.1001/archderm.141.3.389-bDOI Listing

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Article Synopsis
  • A two-year-old girl experienced misdiagnoses such as tinea corporis and psoriasis, leading to ineffective treatments until a proper evaluation revealed her low zinc levels.
  • After being diagnosed with AE, she was treated with zinc sulfate, resulting in the complete resolution of her skin lesions within two weeks.
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Acrokeratosis paraneoplastica (Basex syndrome) with trachyonychia preceding the diagnosis of squamous cell carcinoma of the lung.

Dermatol Online J

April 2024

Department of Dermatology, Tulane University, New Orleans USA Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo USA.

Acrokeratosis paraneoplastica (Basex syndrome) is a rare paraneoplastic condition hallmarked by psoriasiform lesion development on acral surfaces, most often related to an underlying squamous cell carcinoma. Patients may also present with nail plate changes. Successful management of this condition can be accomplished by treating the underlying malignancy.

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Concomitant Severe Psoriasis and Bullous Pemphigoid Induced by COVID-19.

Trop Med Infect Dis

February 2023

Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first isolated in Wuhan, China, is currently a pandemic. At the beginning of the pandemic, pulmonary issues were the most discussed and studied. However, now 3 years later, the role of the dermatologist has become increasingly central.

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Acrokeratosis paraneoplastica Bazex is a rare paraneoplastic skin manifestation, typically causing acral psoriasiform lesions. Patients usually show erythematous hyperkeratosis with yellowish, adherent scales on the hands and feet or other acral locations such as ears or nose. We herein report a case of Bazex syndrome in a male patient, who was previously diagnosed with hepatocellular carcinoma.

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