Conjunctival biopsy of anophthalmic socket in sarcoidosis.

Ophthalmic Plast Reconstr Surg

Department of Ophthalmology, Tulane University Health Sciences Center, New Orleans, Louisiana 70112-2699, USA.

Published: March 2005

AI Article Synopsis

  • A 22-year-old black female with a history of eye injuries presented with uveitis and nodules in her left eye, and her right eye had been enucleated.
  • A biopsy of these nodules did not show the expected granulomatous inflammation, but a random biopsy from her anophthalmic socket revealed noncaseating granulomas, confirming a diagnosis of sarcoidosis.
  • This case is significant as it is the first known instance where sarcoidosis was diagnosed through a conjunctival biopsy from an anophthalmic socket, highlighting this method as a reliable, economical diagnostic tool.

Article Abstract

A case of sarcoidosis was diagnosed by a random conjunctival biopsy from an anophthalmic socket. A 22-year-old black female patient presented with anterior and posterior uveitis and subconjunctival nodules in the left eye. Her right eye was enucleated due to a penetrating injury 3 years before admission. Biopsy of subconjunctival nodules in the left eye failed to demonstrate granulomatous inflammation; however, a random conjunctival biopsy from the normal-appearing anophthalmic socket conjunctiva revealed noncaseating granulomas. Conjunctival biopsy is a safe, cost-effective means of diagnosis in sarcoidosis suspects. To our knowledge, this is the first reported case of sarcoidosis confirmed with random conjunctival biopsy from an anophthalmic socket.

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http://dx.doi.org/10.1097/01.iop.0000155851.68195.8cDOI Listing

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