AI Article Synopsis
- The study examined how total parathyroidectomy and autotransplantation affect bone structure in patients with secondary hyperparathyroidism.
- Despite low PTH levels after 12 weeks, low turnover bone disease was observed, indicating that bone resorption still outpaced formation a year post-surgery.
- Long-term monitoring of bone mineral density is crucial due to these findings, as patients may experience significant decreases in bone density over time.
Article Abstract
Impacts of total parathyroidectomy and autotransplantation on bone histology were evaluated in secondary hyperparathyroidism. Low turnover bone disease accompanied with fibrous tissue developed at 4 weeks after surgery, and osteoclasts disappeared. In addition, fibrous tissue also disappeared at 12 weeks. Even though serum PTH level indicated quite low in some cases, bone resorption exceeded bone formation at 1 years after surgery. So we should pay special attention to the decrease in bone mineral density in the long term in these cases.
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