Sister chromatid exchange (SCE) is a sensitive indicator of genotoxicity. In this study we investigated the effects of alcohol consumption and cigarette smoking on the frequency of SCE in cultures of peripheral lymphocytes. The rate was higher in alcoholics who smoked (10.89+/-2.46) and in smokers (positive controls) (7.64+/-1.01) than in healthy non-smokers (negative controls) (6.96+/-2.18). Statistical analysis suggested that the increases were related to alcohol consumption and cigarette smoking (p<0.05).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cellbi.2004.11.019 | DOI Listing |
Publication Analysis
Top Keywords
sister chromatid
8
peripheral lymphocytes
8
alcohol consumption
8
consumption cigarette
8
cigarette smoking
8
increased frequency
4
frequency sister
4
chromatid exchanges
4
exchanges peripheral
4
lymphocytes alcoholics
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!