As part of an ongoing study of the medicinal plants of the Yucatec Maya, Casimiroa tetrameria was investigated for its phytochemistry. From an ethyl acetate partition of an ethanol extract of the leaves, eight flavonoids and a furanocoumarin were isolated and characterised as 5,6,2',3',5',6'-hexamethoxyflavone, 5,6,2',3',6'-pentamethoxyflavone and 5-methoxy-8-(3''-hydroxymethyl-but-2''-enyloxy)-psoralen using a combination of 1H, 13C NMR and NOESY spectroscopy.
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Spasmolytic and antidiarrhoeal properties of the Yucatec Mayan medicinal plant Casimiroa tetrameria.
J Pharm Pharmacol
September 2005
Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, UK.
The Maya of the Yucatán peninsula commonly use the leaves of Casimiroa tetrameria for treating gastrointestinal disorders, notably diarrhoea and dysentery, as well as gastrointestinal cramps. The phytochemical investigation resulted in the isolation of 13 compounds: eight polymethoxylated flavonoids (two as minor components with a main constituent), four flavonoid glycosides and one furanocoumarin. In this study we used two well-established models in order to assess the gastrointestinal effects of C.
View Article and Find Full Text PDFA furanocoumarin and polymethoxylated flavonoids from the Yucatec Mayan plant Casimiroa tetrameria.
Phytochemistry
March 2005
Institute of Pharmaceutical Biology, Stefan-Meier-Str. 19, Albert-Ludwigs University, 79104 Freiburg, Federal Republic of Germany.
As part of an ongoing study of the medicinal plants of the Yucatec Maya, Casimiroa tetrameria was investigated for its phytochemistry. From an ethyl acetate partition of an ethanol extract of the leaves, eight flavonoids and a furanocoumarin were isolated and characterised as 5,6,2',3',5',6'-hexamethoxyflavone, 5,6,2',3',6'-pentamethoxyflavone and 5-methoxy-8-(3''-hydroxymethyl-but-2''-enyloxy)-psoralen using a combination of 1H, 13C NMR and NOESY spectroscopy.
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