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Helping parents to cope with infant regulatory disorders.
Front Child Adolesc Psychiatry
March 2024
Research Department of Behavioural Science and Health, University College London, London, United Kingdom.
The term Regulatory Disorders (RDs) refers to infants and young children who cry a lot, have poorly organised sleep-waking, or whose feeding is impaired. The characteristic they share is a failure to acquire autonomous self-control of these key behaviours, which most children develop in the first postnatal year. The concept of RDs is helpful in highlighting this question of how infant self-regulation is, or isn't, accomplished, in drawing these characteristics together and distinguishing them from others, and in focusing research and clinical attention on a common, but relatively neglected, set of concerns for families.
View Article and Find Full Text PDFIRF5 as a potential immunological biomarker in lung adenocarcinoma.
Transl Cancer Res
December 2024
Department of Oncology, Guangzhou First People's Hospital, Guangzhou, China.
Background: In the clinic, the primary conventional treatments of advanced non-small cell lung cancer (NSCLC) are surgery, radiation therapy, and chemotherapy. In recent years, immune checkpoint inhibitors (ICIs) have shown promise in optimizing therapeutic benefits when combined with other immunotherapies or standard therapies. However, effective biomarkers for distant metastasis or recurrence have yet to be identified, making it difficult to determine the best therapeutic approaches.
View Article and Find Full Text PDFBest Interests and Decisions to Withdraw Life-Sustaining Treatment from a Conscious, Incapacitated Patient.
Camb Q Healthc Ethics
January 2025
Nova Southeastern University Shepard Broad College of Law, Fort Lauderdale, FL, USA.
Conscious but incapacitated patients need protection from both undertreatment and overtreatment, for they are exceptionally vulnerable, and dependent on others to act in their interests. In the United States, the law prioritizes autonomy over best interests in decision making. Yet U.
View Article and Find Full Text PDFHigh-resolution phase-contrast 3D imaging using nano-holotomography typically requires collecting multiple tomograms at varying sample-to-detector distances, usually 3 to 4. This multi-distance approach limits temporal resolution, making it impractical for studies. Moreover, shifting the sample complicates reconstruction, requiring precise alignment, registration, and interpolation to correct for shift-dependent magnification on the detector.
View Article and Find Full Text PDFAbsorption spectroscopy is a widely used non-contact combustion diagnostic technique. HO is frequently used as the target molecule for combustion temperature measurement. However, correcting the baseline in broadened absorption spectroscopy under high pressure remains challenging.
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