Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Inbreeding and Gallbladder Cancer Risk: Homozygosity Associations Adjusted for Indigenous American Ancestry, BMI, and Genetic Risk of Gallstone Disease.
Cancers (Basel)
December 2024
Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany.
Latin Americans have a rich genetic make-up that translates into heterogeneous fractions of the autosomal genome in runs of homozygosity (F) and heterogeneous types and proportions of indigenous American ancestry. While autozygosity has been linked to several human diseases, very little is known about the relationship between inbreeding, genetic ancestry, and cancer risk in Latin Americans. Chile has one of the highest incidences of gallbladder cancer (GBC) in the world, and we investigated the association between inbreeding, GBC, gallstone disease (GSD), and body mass index (BMI) in 4029 genetically admixed Chileans.
View Article and Find Full Text PDFGender and activity disparities in the relationship between circadian syndrome and gallstone disease.
Front Endocrinol (Lausanne)
January 2025
Department of Gastroenterology, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, China.
Objective: To explore the potential correlation between gallstone disease (GSD) prevalence and circadian syndrome (CircS).
Methods: The cross-sectional research utilized data spanning 2017 to March 2020, sourced from the National Health and Nutrition Examination Survey (NHANES). The GSD data were collected via questionnaires, with appropriate sample weights applied to ensure the study population was representative.
Association between metabolic dysfunction associated steatotic liver disease and gallstones in the US population using propensity score matching.
Sci Rep
January 2025
Department of General Surgery, The Affiliated Wuxi Fifth Hospital of Jiangnan University, No. 1215 Guangrui Road, Wuxi, 214005, Jiangsu, China.
The novel diagnostic term Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) requires at least one cardiovascular risk factor for diagnosis. While the relationship between gallstones and Non-Alcoholic Fatty Liver Disease (NAFLD) has been debated, the association between MASLD and gallstones remains unclear. This cross-sectional study aimed to explore this relationship using National Health and Nutrition Examination Survey (NHANES) data from 2017 to 2020.
View Article and Find Full Text PDFAssociations of phthalate and phthalate alternative metabolites in urine with the risk of gallstones in adults: a cross-sectional analysis.
Environ Geochem Health
January 2025
Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, Lanzhou, 730000, Gansu, China.
Article Synopsis
- The study investigates whether phthalates and their alternatives are linked to the occurrence of gallstones, involving 1,735 NHANES participants.
- Individual associations of specific phthalate metabolites (MCOCHP and MHNCH) were found to have a positive correlation with gallstones, particularly in older adults, men, and those with certain health conditions.
- Findings indicate that both traditional phthalates and their alternatives elevate the risk of gallstones, with alternatives posing a greater risk, especially among vulnerable populations like the elderly and those with obesity, hypertension, or diabetes.
Global Burden of Gallbladder Cancer Attributable to Modifiable Risk Factors.
Aliment Pharmacol Ther
January 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Article Synopsis
- Gallbladder cancer (GBC) is increasingly affecting young adults and is linked to 10 key modifiable risk factors, which account for about 75% of cases globally.
- The study found that central obesity, gallstones, and physical inactivity are the top contributors to GBC, particularly impacting women.
- Most cases are preventable, highlighting the importance of addressing metabolic health conditions to reduce the risk of GBC.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!