Little is known about the fate of antimicrobials during common agricultural waste handling procedures. To better define the potential scope of this problem, concentrations of antimicrobials throughout the waste treatment process were estimated based on known antimicrobial usage, and the resulting predictions of high antimicrobial concentrations indicated the need for further investigation. Samples from building pits, a solids settling basin, a holding pond, and soil amended with waste treatment byproducts were therefore analyzed for traditional chemical parameters and macrolide, lincosamide, and tetracycline antimicrobials. Substantial improvements in water quality were observed during the treatment process. While the macrolide tylosin was not detected, chlortetracycline, oxytetracycline, and lincomycin were found at high concentrations throughout the waste treatment process. Oxytetracycline and lincomycin were also detected in soil from a field amended with waste treatment byproducts.
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