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External damp environment aggravates diarrhea in spleen deficiency and dampness syndrome in mice: involvement of small intestinal contents microbiota, energy metabolism, gastrointestinal and fluid functions.
Front Cell Infect Microbiol
November 2024
College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Objectives: Recent studies have increasingly demonstrated that a multiplatform water environment combined with lard gavage is an effective method for establishing a mouse model of diarrhea. However, the interactions between intestinal microorganisms and diarrhea, as well as the relationships among energy metabolism, fluid balance, and gastrointestinal function in this model, remain poorly understood.
Methods: Building on previous research, this study aimed to optimiz and replicate a multiplatform water environment combined with a lard gavage model.
Characteristics of Gut Microbiome in the Murine Model of Pancreatic Cancer with Damp-Heat Syndrome.
Biomedicines
October 2024
Zhejiang Cancer Hospital, Hangzhou 310022, China.
Article Synopsis
- - The study aimed to create murine models of pancreatic cancer that mimic damp-heat syndrome to investigate differences in gut bacteria composition for potential evaluation markers.
- - Thirty-four male mice were divided into four groups, with some exposed to high-fat diets and environmental stressors to induce symptoms akin to traditional damp-heat syndrome, leading to accelerated tumor growth and inflammation.
- - Findings indicated that the CDHS and CC groups displayed significant health issues and increased pathogenic bacteria, suggesting the potential of intestinal flora in evaluating conditions related to pancreatic cancer and damp-heat syndrome.
Insights into uncovered public health risks. The case of asthma attacks among archival workers: a cross-sectional study.
Front Public Health
September 2024
School of Public Health, Qingdao University, Qingdao, China.
Objective: To ascertain the prevalence of asthma attacks among archivists and identify the associated occupational factors in this understudied professional population.
Methods: We conducted a cross-sectional, questionnaire-based study among 1,002 archival workers. A multiple logistic regression was conducted to identify the association between asthma attacks and occupational exposures.
Receptors on Microglia.
Adv Neurobiol
August 2024
Faculty of Life Sciences, The University of Manchester, Manchester, UK.
Article Synopsis
- Microglial cells are key immune cells in the central nervous system that express a variety of receptors related to both immune functions and neural activities.
- These receptors enable microglia to monitor brain health and actively regulate neural activity and plasticity.
- Additionally, microglial cells help protect the CNS against pathogens and maintain overall function and integrity.
Numerical computation of heat transfer, moisture transport and thermal comfort through walls of buildings made of concrete material in the city of Douala, Cameroon: An investigation.
Heliyon
July 2024
Laboratory of Mechanics, University of Douala, Douala, Cameroon.
The buildings of the city of Douala in Cameroon have been experiencing degradation for several decades due to the climate characterized by high humidity and oppressive heat. As a result, large grayish or black stains can be observed on these buildings. We sometimes witness the subsidence of the slab of the balconies, the cracking of the walls and the collapse of the buildings worn by the humidity.
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