Objective: To evaluate the complications and prosthesis survival associated with implantation of the Mentor Alpha-1 inflatable penile prosthesis (IPP) for the treatment of erectile dysfunction (ED).
Material And Methods: Between August 1995 and March 2003, 65 patients underwent implantation of a Mentor Alpha-1 IPP at the Urological Departments of Skejby or Aalborg University Hospitals. Patient data were obtained retrospectively from medical files.
Results: The follow-up period ranged from 1 to 96 months (median 48.5 months). Twenty-one patients (32%) experienced complications that required revision. The majority of complications consisted of mechanical problems, but infection was also a large contributor to the complication rate. Seven patients (11%) had the prosthesis permanently removed due to infection. Kaplan-Meier estimates of the 5-year prosthesis survival rates with and without successful revisions due to complications were 88% and 63%, respectively.
Conclusions: The Mentor Alpha-1 IPP is an efficient treatment for ED in situations where less invasive therapy has failed. The risk of infection or mechanical failure must not be ignored. Patients should be informed of this risk before agreeing to implantation surgery.
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http://dx.doi.org/10.1080/00365590410018747 | DOI Listing |
Anim Sci J
August 2022
College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
We investigated the expression of epidermal growth factor receptor (EGFR), Type I collagen α1 chain (COL1A1), and caveolin 1 (CAV1) during follicular development and examined the regulatory role of melatonin (MLT) on EGFR, COL1A1, and CAV1 in sheep antral ovaries. The expression was detected in granulosa and theca cells by immunohistochemistry. Quantitative real-time polymerase chain reaction and Western blotting were used to examine the expression levels of EGFR, COL1A1, and CAV1 in small (≤2 mm), medium (2-5 mm), and large (≥5 mm) follicles.
View Article and Find Full Text PDFInt J Chron Obstruct Pulmon Dis
January 2019
Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, IL 60208, USA.
Background: Swallowing impairment (dysphagia) has been associated with COPD and may contribute to exacerbations of this chronic and progressive disease. Further, risk of mortality increases with concomitant presence of cachexia in the COPD population. The purpose of this prospective study was to depict oropharyngeal swallowing physiology in underweight patients with stable but advanced-stage COPD.
View Article and Find Full Text PDFJ Sex Med
June 2012
Regional Urology, Shreveport, LA, USA.
Introduction: This study was conducted to determine how long after inflatable penile prosthesis (IPP) surgery patients attempt sexual intercourse and the frequency of subsequent relations. We also examined survival-related factors for the AMS 700 CX, Mentor Alpha 1, and Mentor Alpha Narrow Base.
Aims: The aim was to survey men who received IPPs and collect information about their return to sexual function and frequency of use, and to assess the resilience of their devices.
Xenotransplantation
November 2010
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA.
The author pays tribute to those who stimulated him to follow a career in clinical cardiothoracic surgery and experimental transplantation. Highlights of his career have been in contributing to (i) the first hypothermic perfusion storage of the donor heart to be used successfully in clinical practice, (ii) hormonal therapy in the management of the brain-dead potential organ donor, (iii) the identification of Gal alpha 1,3Gal as the major antigenic target for primate natural anti-pig antibodies, (iv) the 2- to 6-month survival of alpha1,3-galactosyltransferase gene-knockout hearts transplanted into baboons, and (v) the 3- to 12-month normoglycemia following the transplantation of islets from CD46-transgenic pigs into diabetic monkeys. Many friends have been made through a mutual interest in transplantation, particularly through the activities of the International Xenotransplantation Association (IXA).
View Article and Find Full Text PDFJ Sex Med
December 2008
Division of Urology, West Virginia University, Morgantown, WV 26506, USA.
Introduction: Erosion of penile prosthesis tubing represents a late complication of penile prosthesis surgery. To our knowledge, this is the first report of isolated erosion of penile implant pump tubing into the urethra in an otherwise asymptomatic patient. The patient had no signs of infection or erosion and no voiding complaints.
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