[A novel orthopaedic biodegradable polymer and its biocompatibility].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

Department of Orthopedic Surgery, The First Teaching Hospital of JiLin University, Changchun 130021, China.

Published: February 2005

Copolymer of polycaprolactone (PCL) and polylactic acid (PLA) was synthesized and catalyzed using Y (CF3COO)3/AL (I-Bu)3. The biocompatibility was evaluated by means of biochemistry, immunocytochemistry, and by cytotoxity test. This novel orthopedic biodegradable polymer can serve as an ideal orthopedic biodegradable implants, and adjustment of molecular weight and ratio of polymers can control its degradation period.

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