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Importance of early use of tolvaptan in hyponatremic acutely decompensated heart failure patients, a retrospective study.
Egypt Heart J
January 2025
Department of Cardiology, Division of Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Background: Hyponatremia is one of the complicating findings in acute decompensated heart failure. Decrease in cardiac output and systemic blood pressure triggers activation of renin-angiotensin-aldosterone system, antidiuretic hormone, and norepinephrine due to the perceived hypovolemia. Fluid-overloaded heart failure patients are commonly treated with loop diuretics, acutely decompensated heart failure patients tend to be less responsive to conventional oral doses of a loop diuretic, while other different diuretics could work in different part of nephron circulation system.
View Article and Find Full Text PDFPathophysiology and management of postural orthostatic tachycardia syndrome (POTS): A literature review.
Curr Probl Cardiol
December 2024
Department of Cardiovascular Medicine, National Kapodistrian University of Athens, Athens, Greece; Department of Cardiovascular Medicine, Section of Heart Failure and Transplantation, University of Iowa, Iowa City, IA, USA. Electronic address:
Postural Orthostatic Tachycardia Syndrome (POTS) is a form of cardiovascular autonomic disorders characterized by orthostatic intolerance and a symptomatic increase in heart rate upon standing, which can significantly impair patients' quality of life. Its pathophysiology is complex, multifactorial; thus, a variety of treatment approaches have been investigated. Recent studies have identified three primary POTS phenotypes-hyperadrenergic, neuropathic, and hypovolemic-each requiring tailored management strategies.
View Article and Find Full Text PDFRates, Risk Factors, and Outcomes of Nonvariceal Upper Gastrointestinal Bleeding in Patients Hospitalized for COVID-19 in the United States.
Curr Med Sci
December 2024
Department of Medicine, University of Minnesota/Minneapolis VA Medical Center, Minneapolis, 55417, USA.
Article Synopsis
- The study looked at how often and why non-variceal upper gastrointestinal bleeding (NVUGIB) occurs in hospitalized COVID-19 patients, as well as the impact of this condition on patient outcomes.
- Among over a million hospitalized patients, 1.87% experienced NVUGIB, with Asian Americans at the highest risk followed by other racial groups, and patients with higher Charlson Comorbidity Index scores also faced increased risk.
- COVID-19 patients who developed NVUGIB had significantly worse outcomes, including much higher rates of mortality and severe complications like kidney injury and cardiac arrest, highlighting the need for better prevention strategies.
Persistent and severe hypotension during radical transabdominal ovarian cancer surgery: A case report.
Medicine (Baltimore)
December 2024
Department of Anesthesiology, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, China.
Rationale: In radical surgery for ovarian cancer (OC), hypotension that is difficult to correct is usually rare unless there is significant blood loss. We recently encountered a patient who developed persistent and severe hypotension during radical transabdominal OC surgery.
Patient Concerns: A patient was 52 years old with a history of hypertension and well-controlled preoperative blood pressure (BP).
A novel wearable bioimpedance sensor for continuous monitoring of fluid balance: a study on isotonic hypovolemia in healthy adults.
J Clin Monit Comput
December 2024
Mode Sensors AS, Trondheim, Norway.
Purpose: This study aimed to investigate the ability of a novel wearable bioimpedance sensor to monitor changes in fluid balance induced by furosemide. Because iso-osmotic fluid loss is expected to primarily comprise fluid from the extracellular compartment it was hypothesized that isotonic hypovolemia would increase the extracellular resistance (R).
Methods: 27 healthy adults (20 women, 7 men; 35 ± 10 year.
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