AI Article Synopsis
- The study analyzed non-Hodgkin lymphoma (NHL) patterns in Chinese migrants to British Columbia using data from 1980 to 1997.
- The incidence rate of NHL in migrants was found to be lower (7.11 per 100,000) compared to populations in Hong Kong (7.91) and British Columbia (11.88).
- Genetic factors likely play a larger role in the incidence of NHL in Chinese individuals, while some lymphoma subtypes may exhibit decreased rates due to environmental influences.
Article Abstract
The incidence and spectrum of non-Hodgkin lymphoma (NHL) differ between the Chinese and Caucasian populations. Using population-based registries, we studied the pattern of NHL in Chinese migrants to British Columbia (BC). The records of all NHL cases of Chinese descent diagnosed between 1980 and 1997 were retrieved. Age-standardized incidences were calculated by 5-year intervals in terms of age and calendar years and the relative rates were compared between the migrant, Hong Kong and BC populations. The histological distribution of NHL was compared with 4500 consecutive NHL cases diagnosed in the two populations. A total of 211 cases of migrant NHL were identified, with an age-standardized incidence rate of 7.11 per 100 000 per year, compared with the Hong Kong and BC rates of 7.91 [standardized incidence ratio (SIR) = 0.86, P = 0.01] and 11.88 (SIR = 0.56, P < 0.01). The standardized rates of follicular lymphoma remained low, but the incidence of gastric and nasal natural killer/T lymphomas in migrants were lower than expected. Genetic factors appeared to be stronger than environmental factors in governing the overall incidence of NHL in Chinese. However, certain subtypes of lymphoma may show decreased rates in migrants because of environmental factors.
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| http://dx.doi.org/10.1111/j.1365-2141.2005.05387.x | DOI Listing |
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