Dithranol irritation in psoriasis treatment: a study of 68 inpatients.

J Eur Acad Dermatol Venereol

Department of Dermatology, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

Published: March 2005

The irritant response of perilesional skin is a serious limitation of dithranol therapy in psoriasis. No data are available on the actual prevalence and severity of irritation during 24-h dithranol treatment in an inpatient setting. Using a retrospective analysis of 68 patients with psoriasis visiting our inpatient department for dithranol treatment, the occurrence of dithranol irritation was studied. We found a relatively high frequency of dithranol irritation. Furthermore, most irritation occurs at the start of the therapy with relatively low concentrations.

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http://dx.doi.org/10.1111/j.1468-3083.2005.01093.xDOI Listing

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