A total of 3,023 clinical specimens were tested for Neisseria gonorrhoeae by using COBAS AMPLICOR (CA) PCR and confirmation of positives by N. gonorrhoeae-specific 16S rRNA PCR. The sensitivity of CA plus 16S rRNA PCR was 98.8%, compared to 68.2% for culture. Confirmation of CA positives increased the positive predictive value from 54.8 to 96.6%.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1081235 | PMC |
| http://dx.doi.org/10.1128/JCM.43.3.1445-1447.2005 | DOI Listing |
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